{"id":"xibornol","rwe":[{"pmid":"35699841","year":"2023","title":"In Vitro Potential Virucidal Effect Evaluation of Xibornol on Human Adenovirus Type 5, Human Rhinovirus Type 13, Human Coronavirus 229E, Human Parainfluenza Virus Type 1, and Human Respiratory Syncytial Virus.","finding":"","journal":"Advances in experimental medicine and biology","studyType":"Clinical Study"},{"pmid":"34387849","year":"2022","title":"Antimicrobial Activity of Xibornol and a Xibornol-Based Formulation Against Gram-Positive Pathogens of the Respiratory Tract.","finding":"","journal":"Advances in experimental medicine and biology","studyType":"Clinical Study"},{"pmid":"17531411","year":"2007","title":"Liquid spray formulations of xibornol by using self-microemulsifying drug delivery systems.","finding":"","journal":"International journal of pharmaceutics","studyType":"Clinical Study"},{"pmid":"3396117","year":"1988","title":"Activity of xibornol against Staphylococcus aureus.","finding":"","journal":"Chemioterapia : international journal of the Mediterranean Society of Chemotherapy","studyType":"Clinical Study"},{"pmid":"3366502","year":"1988","title":"Non-interference of xibornol on the theophylline blood levels.","finding":"","journal":"International journal of clinical pharmacology research","studyType":"Clinical Study"}],"tags":[{"label":"xibornol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"J01XX02","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"bactacine","offLabel":[],"synonyms":["xibornol","bactacine","nanbacine"],"timeline":[],"approvals":[],"brandName":"Bactacine","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"xibornol","explanation":"Unfortunately, the exact way Bactacine works is not well understood, but it is thought to affect the body's response to certain stimuli. This can lead to changes in how the body functions, which may help to treat certain conditions. However, more research is needed to fully understand its mechanism of action.","oneSentence":"Bactacine works by interacting with a specific biological target to produce its therapeutic effect.","technicalDetail":"The technical details of Bactacine's mechanism of action are not available, as its target and pharmacological properties are unknown."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2851","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=XIBORNOL","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T16:15:14.401751","biosimilars":[],"competitors":[{"drugName":"fosfomycin","drugSlug":"fosfomycin","fdaApproval":"1996-12-19","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"spectinomycin","drugSlug":"spectinomycin","fdaApproval":"1971-06-30","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"methenamine","drugSlug":"methenamine","fdaApproval":"1967-07-05","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"linezolid","drugSlug":"linezolid","fdaApproval":"2000-04-18","genericCount":24,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"daptomycin","drugSlug":"daptomycin","fdaApproval":"2003-09-12","patentExpiry":"Sep 4, 2028","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"bacitracin","drugSlug":"bacitracin","fdaApproval":"1948-07-29","genericCount":10,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"tedizolid phosphate","drugSlug":"tedizolid-phosphate","fdaApproval":"2014-06-20","patentExpiry":"Jun 20, 2028","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"lefamulin","drugSlug":"lefamulin","fdaApproval":"2019-08-19","patentExpiry":"May 23, 2031","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"xibornol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"fosfomycin","brandName":"fosfomycin","genericName":"fosfomycin","approvalYear":"1996","relationship":"same-class"},{"drugId":"spectinomycin","brandName":"spectinomycin","genericName":"spectinomycin","approvalYear":"1971","relationship":"same-class"},{"drugId":"methenamine","brandName":"methenamine","genericName":"methenamine","approvalYear":"1967","relationship":"same-class"},{"drugId":"linezolid","brandName":"linezolid","genericName":"linezolid","approvalYear":"2000","relationship":"same-class"},{"drugId":"daptomycin","brandName":"daptomycin","genericName":"daptomycin","approvalYear":"2003","relationship":"same-class"},{"drugId":"bacitracin","brandName":"bacitracin","genericName":"bacitracin","approvalYear":"1948","relationship":"same-class"},{"drugId":"tedizolid-phosphate","brandName":"tedizolid 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Human Coronavirus 229E, Human Parainfluenza Virus Type 1, and Human Respiratory Syncytial Virus.","journal":"Advances in experimental medicine and biology"},{"date":"2022","pmid":"34387849","title":"Antimicrobial Activity of Xibornol and a Xibornol-Based Formulation Against Gram-Positive Pathogens of the Respiratory Tract.","journal":"Advances in experimental medicine and biology"},{"date":"2007 Aug 1","pmid":"17531411","title":"Liquid spray formulations of xibornol by using self-microemulsifying drug delivery systems.","journal":"International journal of pharmaceutics"},{"date":"1988 Apr","pmid":"3396117","title":"Activity of xibornol against Staphylococcus aureus.","journal":"Chemioterapia : international journal of the Mediterranean Society of Chemotherapy"},{"date":"1988","pmid":"3366502","title":"Non-interference of xibornol on the theophylline blood levels.","journal":"International journal of clinical pharmacology research"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bactacine is a small molecule with the synonyms 6-ISOBORNYL-3,4-XYLENOL, XIBORNOL, and XIBORNOL.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}