{"id":"xenetix-ct-perfusion-imaging","safety":{"commonSideEffects":[{"rate":null,"effect":"Contrast-induced nephropathy"},{"rate":null,"effect":"Allergic reaction (mild to moderate)"},{"rate":null,"effect":"Nausea and vomiting"},{"rate":null,"effect":"Flushing and warmth sensation"},{"rate":null,"effect":"Thyroid dysfunction (iodine-related)"}]},"_chembl":{"chemblId":"CHEMBL4297274","moleculeType":"Small molecule","molecularWeight":"533.80"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Xenetix contains iopamidol, a non-ionic iodinated contrast agent that distributes through the vasculature and extracellular space. The iodine atoms attenuate X-rays, creating enhanced contrast between perfused and non-perfused tissues on CT scans. This allows quantitative assessment of regional blood flow and tissue perfusion in organs such as the brain, heart, and lungs.","oneSentence":"Xenetix is an iodinated contrast medium that enhances visualization of blood perfusion in tissues during CT imaging by increasing radiodensity in vascular and tissue compartments.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:16:15.557Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"CT perfusion imaging of the brain for acute stroke evaluation"},{"name":"CT perfusion imaging of the heart for myocardial ischemia assessment"},{"name":"CT perfusion imaging of solid organs for tumor characterization and tissue viability assessment"}]},"trialDetails":[{"nctId":"NCT01639703","phase":"PHASE4","title":"Hepatic Xenetix-CT Perfusion","status":"COMPLETED","sponsor":"Guerbet","startDate":"2012-04","conditions":"Hepatocellular Carcinoma","enrollment":96}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":12704,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Xenetix-CT perfusion imaging","genericName":"Xenetix-CT perfusion imaging","companyName":"Guerbet","companyId":"guerbet","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Xenetix-CT perfusion imaging is a diagnostic technique used to assess hepatocellular carcinoma. It involves the use of a small molecule, CT 2584, to evaluate blood flow in the liver.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}