{"id":"wf10","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL4299960","moleculeType":"Small molecule","molecularWeight":"305.83"},"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"WF10 works by activating macrophages and enhancing the body's natural immune response while simultaneously reducing oxidative stress and inflammatory mediators. It has been investigated for its ability to modulate immune function in conditions characterized by immune dysfunction or excessive inflammation, particularly in wound healing and tissue repair contexts.","oneSentence":"WF10 is a stable, diluted solution of dihydroxyethyl disulfide that acts as an immunomodulator and antioxidant to enhance immune function and reduce inflammatory responses.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:40:58.771Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Wound healing and tissue repair"},{"name":"Immune dysfunction disorders"}]},"trialDetails":[{"nctId":"NCT04372355","phase":"PHASE2","title":"Effect of WF10 (TCDO) on HbA1c Values in Diabetic Foot Ulcer Patients","status":"COMPLETED","sponsor":"Srinakharinwirot University","startDate":"2019-06-19","conditions":"Diabetic Foot Ulcer (DFU), Uncontrolled Diabetes With Foot Ulcer","enrollment":40},{"nctId":"NCT01586468","phase":"PHASE2","title":"PILOT STUDY OF THE EFFICACY AND SAFETY OF WF10 IN SUBJECTS SUFFERING FROM PERSISTENT ALLERGIC RHINITIS","status":"COMPLETED","sponsor":"Nuvo Research GmbH","startDate":"2010-03","conditions":"Allergic Rhinitis","enrollment":60},{"nctId":"NCT00002244","phase":"PHASE3","title":"A Study to Evaluate the Safety and Effectiveness of WF10 Given to Patients With Late-Stage HIV Disease","status":"COMPLETED","sponsor":"OXO Chemie","startDate":"","conditions":"HIV Infections","enrollment":240},{"nctId":"NCT00002119","phase":"PHASE1","title":"A Phase I/II Clinical Study of WF 10 IV Solution ( TCDO ) in Patients With HIV Infection","status":"COMPLETED","sponsor":"Oxo Chemie GmbH","startDate":"","conditions":"HIV Infections","enrollment":""},{"nctId":"NCT00002152","phase":"PHASE2","title":"A Study of WF 10 IV Solution in Patients With Advanced HIV Disease","status":"COMPLETED","sponsor":"Oxo Chemie GmbH","startDate":"","conditions":"HIV Infections","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":34,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Immunokine"],"phase":"phase_3","status":"active","brandName":"WF10","genericName":"WF10","companyName":"Oxo Chemie GmbH","companyId":"oxo-chemie-gmbh","modality":"Small molecule","firstApprovalDate":"","aiSummary":"WF10 is a stable, diluted solution of dihydroxyethyl disulfide that acts as an immunomodulator and antioxidant to enhance immune function and reduce inflammatory responses. Used for Wound healing and tissue repair, Immune dysfunction disorders.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}