{"id":"voltaren-gel","safety":{"commonSideEffects":[{"rate":"5-15","effect":"Application site reactions (erythema, pruritus, irritation)"},{"rate":"1-3","effect":"Photosensitivity"},{"rate":"1-5","effect":"Contact dermatitis"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Diclofenac, the active ingredient in Voltaren Gel, penetrates the skin to inhibit COX-1 and COX-2 enzymes, thereby reducing prostaglandin synthesis in affected tissues. 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