{"id":"voacamine","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"vocamine","offLabel":[],"synonyms":["voacamine","voacanginine","vocamine"],"timeline":[],"approvals":[],"brandName":"Vocamine","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like a city with many different roads and intersections. Vocamine is like a small car that drives along those roads, interacting with the cells in a specific way to produce a desired effect. However, the exact route it takes and how it interacts with the cells is still a mystery.","oneSentence":"Vocamine is thought to work by interacting with specific biological pathways, but the exact mechanism is unknown.","technicalDetail":"Vocamine is a small molecule that likely works by binding to a specific target, such as a protein or receptor, to produce a downstream effect. The exact nature of this interaction is unknown, but it may involve changes in signaling pathways or the regulation of gene expression."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Voacamine","title":"Voacamine","extract":"Voacamine, also known under the older names voacanginine and vocamine, is a naturally occurring dimeric indole alkaloid of the secologanin type, found in a number of plants, including Voacanga africana and Tabernaemontana divaricata. It is approved for use as an antimalarial drug in several African countries. Voacamine exhibits cannabinoid CB1 receptor antagonistic activity."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/5100","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=voacamine","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Voacamine","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T16:09:33.925507","biosimilars":[],"competitors":[],"genericName":"voacamine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"2Z504YT5AG","CHEBI":"CHEBI:10014","UMLSCUI":"C0282813","ChEMBL_ID":"CHEMBL445022","DRUGBANK_ID":"DB04877","PUBCHEM_CID":"90479276","MESH_SUPPLEMENTAL_RECORD_UI":"C005891"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":51,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Voacamine is a naturally occurring small molecule dimeric indole alkaloid found in plants such as Voacanga africana and Tabernaemontana divaricata. It is approved for use as an antimalarial drug in several African countries and has been shown to exhibit cannabinoid CB1 receptor antagonistic activity.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}