{"id":"visnadine","rwe":[{"pmid":"41337159","year":"2025","title":"Evaluation of dihydropyranocoumarins as potent inhibitors against triple-negative breast cancer: An integrated of in silico, quantum & molecular modeling approaches.","finding":"","journal":"PloS one","studyType":"Clinical Study"},{"pmid":"39661778","year":"2025","title":"Identification of novel fructose 1,6-bisphosphate aldolase inhibitors against tuberculosis: QSAR, molecular docking, and molecular dynamics simulation-based analysis of DrugBank compounds.","finding":"","journal":"Journal of biomolecular structure & dynamics","studyType":"Clinical Study"},{"pmid":"38528806","year":"2024","title":"Efficacy and safety of visnadine in the treatment of symptoms of sexual dysfunction in heterosexual women: a systematic review of randomized clinical trials.","finding":"","journal":"Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology","studyType":"Clinical Study"},{"pmid":"31698889","year":"2019","title":"A randomized single-blind placebo-controlled study of a Visnadine Emulgel formulation on healthy postmenopausal women.","finding":"","journal":"Minerva ginecologica","studyType":"Clinical Study"},{"pmid":"31560182","year":"2020","title":"An open trial of a Visnadine emulgel topical application in postmenopausal superficial dyspareunia: daily vs. on-demand use.","finding":"","journal":"Minerva ginecologica","studyType":"Clinical Study"}],"tags":[{"label":"visnadine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C04AX24","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"visnamine","offLabel":[],"synonyms":["visnadine","visnamine","visnacorin"],"timeline":[],"approvals":[],"brandName":"Visnamine","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"visnadine","explanation":"Imagine your cells are like a city with many different buildings and roads. Visnadine is like a messenger that helps the different parts of the city communicate with each other. However, we don't know exactly how it delivers its message or what it's trying to say.","oneSentence":"Visnadine works by interacting with cellular processes, but the exact mechanism is unknown.","technicalDetail":"Visnadine is a small molecule that binds to and modulates the activity of specific cellular targets, although the identity of these targets is currently unknown."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3649","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=VISNADINE","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=VISNADINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T16:14:25.093784","biosimilars":[],"competitors":[{"drugName":"phenoxybenzamine","drugSlug":"phenoxybenzamine","fdaApproval":"1953-01-26","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"visnadine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"phenoxybenzamine","brandName":"phenoxybenzamine","genericName":"phenoxybenzamine","approvalYear":"1953","relationship":"same-class"}],"trialDetails":[{"nctId":"NCT04579991","phase":"NA","title":"Effects of Visnadin, Ethyl Ximeninate, Coleus Barbatus and Millet in Emulgel on Sexual Function in Postmenopausal Women","status":"RECRUITING","sponsor":"Chulalongkorn University","startDate":"2021-05-27","conditions":["Female Sexual Function","Vulvovaginal Atrophy","Postmenopausal Atrophic Vaginitis"],"enrollment":100,"completionDate":"2024-11-25"},{"nctId":"NCT03281655","phase":"PHASE2","title":"Visnadine, Prenylflavonoids and Bovine Colostrum to Treat Vulvovaginal Atrophy in Postmenopausal Women","status":"COMPLETED","sponsor":"University of Messina","startDate":"2016-12","conditions":["Vulvovaginal Atrophy","Menopause"],"enrollment":54,"completionDate":"2018-01"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"0RL4V0K263","CHEBI":"CHEBI:10001","INN_ID":"1832","UMLSCUI":"C0644519","ChEMBL_ID":"CHEMBL3989444","KEGG_DRUG":"D08735","DRUGBANK_ID":"DB13355","PUBCHEM_CID":"442151"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":18,"therapeuticAreas":["Gastroenterology"],"atcClassification":{"source":"DrugCentral","atcCode":"C04AX24","allCodes":["C04AX24"]},"biosimilarFilings":[],"recentPublications":[{"date":"2025","pmid":"41337159","title":"Evaluation of dihydropyranocoumarins as potent inhibitors against triple-negative breast cancer: An integrated of in silico, quantum & molecular modeling approaches.","journal":"PloS one"},{"date":"2025 Sep","pmid":"39661778","title":"Identification of novel fructose 1,6-bisphosphate aldolase inhibitors against tuberculosis: QSAR, molecular docking, and molecular dynamics simulation-based analysis of DrugBank compounds.","journal":"Journal of biomolecular structure & dynamics"},{"date":"2024 Dec","pmid":"38528806","title":"Efficacy and safety of visnadine in the treatment of symptoms of sexual dysfunction in heterosexual women: a systematic review of randomized clinical trials.","journal":"Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology"},{"date":"2019 Oct","pmid":"31698889","title":"A randomized single-blind placebo-controlled study of a Visnadine Emulgel formulation on healthy postmenopausal women.","journal":"Minerva ginecologica"},{"date":"2020 Feb","pmid":"31560182","title":"An open trial of a Visnadine emulgel topical application in postmenopausal superficial dyspareunia: daily vs. on-demand use.","journal":"Minerva ginecologica"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Visnamine is a small molecule. It is also known by the synonyms VISNADIN, VISNADINA, and VISNADINE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}