{"id":"visine-for-contacts","safety":{"commonSideEffects":[{"rate":null,"effect":"Transient stinging or burning"},{"rate":null,"effect":"Rebound redness with prolonged use"},{"rate":null,"effect":"Mydriasis (pupil dilation)"}]},"_chembl":{"chemblId":"CHEMBL521875","moleculeType":"Small molecule","molecularWeight":"460.53"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The active ingredient is tetrahydrozoline hydrochloride, an alpha-adrenergic agonist that causes vasoconstriction of the small blood vessels on the surface of the eye. This reduces blood flow to the conjunctiva, thereby decreasing redness and providing temporary relief from minor eye irritation. The formulation is specifically designed to be compatible with contact lens wear.","oneSentence":"Visine for Contacts is a decongestant eye drop that constricts blood vessels in the eye to reduce redness and irritation.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:15:22.324Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Temporary relief of redness of the eye due to minor irritation in contact lens wearers"}]},"trialDetails":[{"nctId":"NCT01105624","phase":"PHASE4","title":"A Four Week Study of Azithromycin Ophthalmic Solution, 1% Versus Rewetting Drops in Subjects With History and Current Complaint of Contact Lens-Related Dry Eye (CLDE)","status":"COMPLETED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2010-03","conditions":"Contact Lens Dry Eye","enrollment":50}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Visine® for Contacts®","genericName":"Visine® for Contacts®","companyName":"Merck Sharp & Dohme LLC","companyId":"merck","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Visine for Contacts is a small molecule ophthalmic solution used to treat contact lens dry eye. It is a 1% azithromycin solution that has been studied in clinical trials for its effectiveness in managing contact lens-related dry eye.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}