{"id":"vehicle-of-adx-102-topical-dermal-cream","safety":{"commonSideEffects":[{"rate":"null","effect":"Eye irritation"},{"rate":"null","effect":"Skin irritation"}]},"_chembl":{"chemblId":"CHEMBL2108947","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By inhibiting the complement pathway, ADX-102 aims to reduce inflammation and alleviate symptoms associated with various ocular and skin conditions. This mechanism is particularly relevant for conditions characterized by complement-mediated inflammation.","oneSentence":"ADX-102 is a topical dermal cream that targets the complement pathway to reduce inflammation.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:40:20.069Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Vernal keratoconjunctivitis"},{"name":"Atopic keratoconjunctivitis"}]},"trialDetails":[{"nctId":"NCT03445650","phase":"PHASE3","title":"RESET Trial - Part 1 - A Phase 3 Trial in Subjects With Sjögren-Larsson Syndrome (SLS)","status":"COMPLETED","sponsor":"Aldeyra Therapeutics, Inc.","startDate":"2018-07-18","conditions":"Sjogren-Larsson Syndrome","enrollment":11}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Vehicle of ADX-102 Topical Dermal Cream","genericName":"Vehicle of ADX-102 Topical Dermal Cream","companyName":"Aldeyra Therapeutics, Inc.","companyId":"aldeyra-therapeutics-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ADX-102 is a topical dermal cream that targets the complement pathway to reduce inflammation. Used for Vernal keratoconjunctivitis, Atopic keratoconjunctivitis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}