{"id":"vehicle-dentifrice","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It works by physically removing plaque and debris from the teeth, without any pharmacological action. This is achieved through the abrasive properties of the dentifrice's ingredients, which help to clean and whiten the teeth.","oneSentence":"Vehicle Dentifrice is a non-pharmacological agent that cleans and polishes teeth.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:54:54.443Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Oral hygiene"}]},"trialDetails":[{"nctId":"NCT07215767","phase":"PHASE3","title":"Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice","status":"RECRUITING","sponsor":"HALEON","startDate":"2025-09-16","conditions":"Dentin Hypersensitivity","enrollment":850},{"nctId":"NCT01133379","phase":"NA","title":"Tooth Sensitivity Relief by Two Mouthrinses","status":"COMPLETED","sponsor":"Johnson & Johnson Consumer and Personal Products Worldwide","startDate":"2010-05","conditions":"Dentin Sensitivity","enrollment":174}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":39,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Vehicle Dentifrice","genericName":"Vehicle Dentifrice","companyName":"HALEON","companyId":"haleon","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Vehicle Dentifrice is a non-pharmacological agent that cleans and polishes teeth. Used for Oral hygiene.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}