{"id":"varicella-vaccine-tiv","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site reactions (pain, redness, swelling)"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Rash"},{"rate":null,"effect":"Myalgia"},{"rate":null,"effect":"Headache"}]},"_chembl":{"chemblId":"CHEMBL2108573","moleculeType":"Vaccine component"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The varicella component uses live attenuated varicella-zoster virus to induce cellular and humoral immunity against chickenpox. The TIV (trivalent inactivated influenza vaccine) component contains inactivated influenza virus antigens (typically two A strains and one B strain) that trigger antibody production against seasonal influenza. Together, the combination provides simultaneous protection against both varicella and influenza in a single administration.","oneSentence":"This combination vaccine stimulates immune responses against varicella-zoster virus and influenza virus through live attenuated or inactivated viral antigens.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:14:55.232Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of varicella (chickenpox)"},{"name":"Prevention of seasonal influenza"}]},"trialDetails":[{"nctId":"NCT06605625","phase":"","title":"Vaccine Responses in Cancer","status":"ACTIVE_NOT_RECRUITING","sponsor":"Abramson Cancer Center at Penn Medicine","startDate":"2022-11-04","conditions":"Viral Vaccines","enrollment":250},{"nctId":"NCT06038617","phase":"PHASE4","title":"Safety of Simultaneous mRNA COVID-19 Vaccine With Other Childhood Vaccines in Young Children","status":"COMPLETED","sponsor":"Duke 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LLC","startDate":"2005-09","conditions":"Herpes Zoster","enrollment":763},{"nctId":"NCT01581164","phase":"","title":"Studies of the Immune Response to Vaccination After Hematopoietic Stem Cell Transplantation","status":"COMPLETED","sponsor":"University of California, San Francisco","startDate":"2011-12","conditions":"Hematopoietic Stem Cell Transplant","enrollment":12},{"nctId":"NCT00474526","phase":"PHASE3","title":"A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Vaccine In Infants","status":"COMPLETED","sponsor":"Novartis Vaccines","startDate":"2007-03","conditions":"Meningitis, Meningococcal","enrollment":4545},{"nctId":"NCT00806195","phase":"PHASE3","title":"Study to Evaluate the Safety of Novartis MenACWY Conjugate Vaccine When Administered With Routine Infant Vaccinations to Healthy Infants","status":"COMPLETED","sponsor":"Novartis","startDate":"2008-12","conditions":"Meningitis, Meningococcal 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Used for Prevention of varicella (chickenpox), Prevention of seasonal influenza.","enrichmentLevel":3,"visitCount":2,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}