{"id":"varicella-5","safety":{"commonSideEffects":[{"rate":"20-30","effect":"Injection site reactions (erythema, swelling, pain)"},{"rate":"10-15","effect":"Fever"},{"rate":"5-10","effect":"Rash"},{"rate":"5","effect":"Myalgia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The vaccine contains a weakened strain of varicella-zoster virus that replicates in host cells but does not cause disease in immunocompetent individuals. This triggers both humoral (antibody) and cell-mediated immune responses, providing protective immunity against natural varicella-zoster virus infection. The attenuated virus induces long-lasting immunity that prevents or significantly reduces the severity of chickenpox.","oneSentence":"Varicella-5 is a live attenuated varicella-zoster virus vaccine that stimulates immune responses to prevent chickenpox infection.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:14:58.095Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of varicella (chickenpox) in susceptible individuals"}]},"trialDetails":[{"nctId":"NCT02173899","phase":"PHASE4","title":"Immunogenicity and Safety of 2 Doses of Live Attenuated Varicella Vaccine","status":"COMPLETED","sponsor":"Changchun Keygen Biological Products Co., Ltd.","startDate":"2014-06","conditions":"Varicella","enrollment":716}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"varicella-5","genericName":"varicella-5","companyName":"Changchun Keygen Biological Products Co., Ltd.","companyId":"changchun-keygen-biological-products-co-ltd","modality":"Biologic","firstApprovalDate":"","aiSummary":"Varicella-5 is a live attenuated varicella-zoster virus vaccine that stimulates immune responses to prevent chickenpox infection. Used for Prevention of varicella (chickenpox) in susceptible individuals.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}