{"id":"vaginal-gel-hyalogyn","safety":{"commonSideEffects":[{"rate":null,"effect":"Local irritation or discomfort"},{"rate":null,"effect":"Allergic reaction"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Hyaluronic acid is a naturally occurring polysaccharide with high water-binding capacity that mimics the vaginal environment's natural hydration. The gel formulation delivers sustained moisture to vaginal tissues, alleviating symptoms of vaginal dryness and improving tissue comfort and elasticity. This mechanism addresses symptoms associated with atrophic vaginitis and vaginal dryness without hormonal activity.","oneSentence":"HYALOGYN® is a hyaluronic acid-based vaginal gel that provides lubrication and hydration to restore vaginal moisture and elasticity.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:39:07.688Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Vaginal dryness and atrophic vaginitis"},{"name":"Vaginal lubrication and moisture restoration"}]},"trialDetails":[{"nctId":"NCT04560283","phase":"PHASE4","title":"HYDEAL-D® Application for Promoting the Restoration of Sexual Function in the Postpartum Period","status":"COMPLETED","sponsor":"Ospedale Policlinico San Martino","startDate":"2016-09-01","conditions":"Vagina; Anomaly, Puerperium; Disease, Sexual Dysfunction","enrollment":25},{"nctId":"NCT01738152","phase":"NA","title":"Non-Hormonal Vaginal Moisturizer in Hormone-Receptor Positive Postmenopausal Cancer Survivors Experiencing Estrogen Deprivation Symptoms on Vulvovaginal Health","status":"COMPLETED","sponsor":"Memorial Sloan Kettering Cancer Center","startDate":"2012-11","conditions":"Breast Cancer, Endometrial Cancer","enrollment":106},{"nctId":"NCT04245293","phase":"NA","title":"Clinical Trial Study To Evaluate The Performance And Safety Of Ainara®","status":"COMPLETED","sponsor":"Italfarmaco","startDate":"2019-04-11","conditions":"Vaginal Disease","enrollment":50}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Vaginal gel HYALOGYN®","genericName":"Vaginal gel HYALOGYN®","companyName":"Ospedale Policlinico San Martino","companyId":"ospedale-policlinico-san-martino","modality":"Small molecule","firstApprovalDate":"","aiSummary":"HYALOGYN® is a hyaluronic acid-based vaginal gel that provides lubrication and hydration to restore vaginal moisture and elasticity. Used for Vaginal dryness and atrophic vaginitis, Vaginal lubrication and moisture restoration.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}