{"id":"vaccinate-with-dt","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain, redness, or swelling"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Myalgia"},{"rate":null,"effect":"Fatigue"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The DT vaccine contains inactivated diphtheria and tetanus toxoids (toxins rendered harmless), which trigger the adaptive immune response to generate antibodies and memory cells. Upon exposure to wild-type Corynebacterium diphtheriae or Clostridium tetani, these pre-formed antibodies neutralize the bacterial toxins before they can cause systemic disease. This is a toxoid-based immunization strategy that has been standard public health practice for decades.","oneSentence":"DT vaccine stimulates the immune system to produce antibodies against diphtheria and tetanus toxins, providing protective immunity against these bacterial diseases.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:38:40.813Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of diphtheria"},{"name":"Prevention of tetanus"}]},"trialDetails":[{"nctId":"NCT05870618","phase":"PHASE4","title":"Immunogenicity and Safety of DTaP or DT Vaccine in 6 Year Old Children","status":"UNKNOWN","sponsor":"Zhejiang Provincial Center for Disease Control and Prevention","startDate":"2023-05","conditions":"Vaccine Reaction","enrollment":480},{"nctId":"NCT05870631","phase":"PHASE4","title":"Immunogenicity and Safety of DTaP or DT Vaccine in 6 Year Old Children ( DTaP/DT )","status":"UNKNOWN","sponsor":"Zhejiang Provincial Center for Disease Control and Prevention","startDate":"2023-05","conditions":"Vaccine Reaction","enrollment":480},{"nctId":"NCT01546909","phase":"PHASE4","title":"Antibody Persistence to REVAXIS or DT Polio and Immune Response to TETRAVAC-ACELLULAIRE","status":"COMPLETED","sponsor":"Sanofi Pasteur, a Sanofi Company","startDate":"2012-02","conditions":"Diphtheria, Tetanus, Poliomyelitis","enrollment":278}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":865,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"vaccinate with DT","genericName":"vaccinate with DT","companyName":"Zhejiang Provincial Center for Disease Control and Prevention","companyId":"zhejiang-provincial-center-for-disease-control-and-prevention","modality":"Biologic","firstApprovalDate":"","aiSummary":"DT vaccine stimulates the immune system to produce antibodies against diphtheria and tetanus toxins, providing protective immunity against these bacterial diseases. Used for Prevention of diphtheria, Prevention of tetanus.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}