{"id":"usual-insulin-treatment","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Hypoglycemia"},{"rate":"10-20%","effect":"Weight gain"},{"rate":"null","effect":"Allergic reactions"}]},"_chembl":null,"_fixedAt":"2026-03-30T12:10:55.571304","_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Insulin binds to the insulin receptor on the surface of cells, triggering a cascade of intracellular signaling events that ultimately lead to the uptake of glucose from the bloodstream into cells. This process is essential for maintaining normal blood glucose levels and preventing hyperglycemia.","oneSentence":"Insulin works by stimulating glucose uptake in cells, thereby lowering blood glucose levels.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:53:45.032Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Type 1 diabetes"},{"name":"Type 2 diabetes"}]},"_fixedFields":["pubmed(6)"],"trialDetails":[{"nctId":"NCT07491133","phase":"NA","title":"Effect of Ambient Temperature on Blood Glucose and Insulin Absorption in Adults With Type 1 Diabetes","status":"NOT_YET_RECRUITING","sponsor":"Institut de Recherches Cliniques de Montreal","startDate":"2026-03","conditions":"Type 1 Diabetes Mellitus","enrollment":30},{"nctId":"NCT03527537","phase":"PHASE4","title":"Gestational Diabetes and Pharmacotherapy (GAP)","status":"ACTIVE_NOT_RECRUITING","sponsor":"Medical College of Wisconsin","startDate":"2021-05-04","conditions":"Gestational Diabetes","enrollment":416},{"nctId":"NCT07460336","phase":"NA","title":"Effects of Cofrogliptin on Beta-Cell Function in LADA Patients","status":"NOT_YET_RECRUITING","sponsor":"Second Xiangya Hospital of Central South University","startDate":"2026-03-15","conditions":"Latent Autoimmune Diabetes in Adults (LADA)","enrollment":84},{"nctId":"NCT06198725","phase":"NA","title":"Intervention for Children With Type 1 Diabetes Targeting Gut Microbes","status":"RECRUITING","sponsor":"Children's Hospital of Fudan University","startDate":"2024-01-08","conditions":"Type 1 Diabetes","enrollment":110},{"nctId":"NCT07472920","phase":"NA","title":"Empagliflozin Adjunctive Therapy in Bipolar Depression","status":"NOT_YET_RECRUITING","sponsor":"University of Sao Paulo","startDate":"2026-03-09","conditions":"Bipolar Disorder, Bipolar Depression, Insulin Resistance","enrollment":20},{"nctId":"NCT07212179","phase":"NA","title":"Safety and Feasibility of a Self-Learning Bolus Calculator With Simplified Meal Announcement in Adolescents With Type 1 Diabetes Using Automated Insulin Delivery","status":"RECRUITING","sponsor":"Anas El Fathi","startDate":"2026-03-03","conditions":"Type 1 Diabetes","enrollment":6},{"nctId":"NCT06579404","phase":"NA","title":"Closed-loop in Adults With Type 2 Diabetes","status":"RECRUITING","sponsor":"University of Cambridge","startDate":"2024-12-06","conditions":"Type 2 Diabetes Treated With Insulin","enrollment":224},{"nctId":"NCT07329088","phase":"NA","title":"Isoleucine Addition Treatment Effects in a Controlled Diet Study","status":"NOT_YET_RECRUITING","sponsor":"Jean L. Fry","startDate":"2026-05-04","conditions":"Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Metabolic Syndrome (MetS), Obesity & Overweight","enrollment":40},{"nctId":"NCT02088658","phase":"NA","title":"Technology Intensified Diabetes Education Study in African Americans","status":"COMPLETED","sponsor":"State University of New York at Buffalo","startDate":"2013-05","conditions":"Diabetes Mellitus, Type 2, Diabetes Mellitus, Adult-Onset, Diabetes Mellitus, Non-Insulin-Dependent","enrollment":200},{"nctId":"NCT07455643","phase":"NA","title":"Closed-loop Response to Unannounced Mixed and Carbohydrates-rich Breakfasts","status":"COMPLETED","sponsor":"University of Catania","startDate":"2025-04-20","conditions":"Type 1 Diabetes Mellitus","enrollment":20},{"nctId":"NCT07451561","phase":"NA","title":"Role of Combination Therapy of Glucose Insulin Potassium Infusion (GIK), Intravenous Hydrocortisone and Oral Sevelamer in Treatment of Acute Aluminum Phosphide Poisoned Cases Admitted to Intensive Care Unit (ICU) at Sohag University Hospitals.","status":"NOT_YET_RECRUITING","sponsor":"Sohag University","startDate":"2026-03","conditions":"Acute Aluminum Phosphide Poisoned Cases","enrollment":74},{"nctId":"NCT07430293","phase":"NA","title":"Hybrid Closed-Loop Insulin Delivery After Pancreatectomy","status":"NOT_YET_RECRUITING","sponsor":"Centre Hospitalier Sud Francilien","startDate":"2026-03-01","conditions":"Pancreatectomy, Total Pancreatectomy, Partial Pancreatectomy","enrollment":24},{"nctId":"NCT06449677","phase":"PHASE3","title":"Bionic Pancreas in CFRD","status":"RECRUITING","sponsor":"Jaeb Center for Health Research","startDate":"2024-09-24","conditions":"Cystic Fibrosis-related Diabetes","enrollment":150},{"nctId":"NCT05562492","phase":"NA","title":"Closed-loop for People Living With Cystic Fibrosis Related Diabetes","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Cambridge","startDate":"2023-04-12","conditions":"Cystic Fibrosis-related Diabetes","enrollment":128},{"nctId":"NCT07287943","phase":"NA","title":"To Study the Efficacy and Safety of Medtronic 780G Insulin Pump in People With Gastroparesis and Type 1 Diabetes.","status":"RECRUITING","sponsor":"Viral N. Shah","startDate":"2026-02-09","conditions":"Type 1 Diabetes, Gastroparesis Due to Diabetes Mellitus Type I","enrollment":34},{"nctId":"NCT07059091","phase":"PHASE2","title":"Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD","status":"RECRUITING","sponsor":"Johns Hopkins University","startDate":"2026-02-12","conditions":"Chronic Obstructive Pulmonary Disease (COPD), Allergies","enrollment":334},{"nctId":"NCT06330194","phase":"NA","title":"Next Generation Advanced Insulin Delivery System in Adults With Diabetes and Advanced Renal Disease","status":"COMPLETED","sponsor":"Steno Diabetes Center Copenhagen","startDate":"2024-04-18","conditions":"Dialysis, Chronic Kidney Disease, Diabetes Mellitus, Type 2","enrollment":15},{"nctId":"NCT01794143","phase":"PHASE3","title":"A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes","status":"COMPLETED","sponsor":"GRADE Study Group","startDate":"2013-05","conditions":"Type 2 Diabetes, Comparative Effectiveness of Glycemia-lowering Medications","enrollment":7850},{"nctId":"NCT06420661","phase":"NA","title":"School Partnered Collaborative Care (SPACE) Intervention for Children With Type 1 Diabetes","status":"ENROLLING_BY_INVITATION","sponsor":"University of Pittsburgh","startDate":"2024-08-21","conditions":"Type 1 Diabetes","enrollment":30},{"nctId":"NCT07226128","phase":"NA","title":"The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV","status":"NOT_YET_RECRUITING","sponsor":"Indiana University","startDate":"2026-02-15","conditions":"HIV, Depression in Adults, Insulin Resistance","enrollment":150},{"nctId":"NCT06185296","phase":"NA","title":"The Intelligent Diabetes TelemonitoRing Using Decision Support to Treat Patients on Insulin Therapy","status":"RECRUITING","sponsor":"Aalborg University Hospital","startDate":"2025-11-15","conditions":"Type 2 Diabetes Treated With Insulin","enrollment":51},{"nctId":"NCT07377448","phase":"","title":"Insulin Use and Respiratory Muscle Strength in Type 2 Diabetes","status":"COMPLETED","sponsor":"Izmir Bakircay University","startDate":"2025-01-02","conditions":"Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 2 Treated With Insulin","enrollment":70},{"nctId":"NCT03866408","phase":"EARLY_PHASE1","title":"Insulin Regulation of Lipolysis and Lipolysis Proteins","status":"RECRUITING","sponsor":"Mayo Clinic","startDate":"2018-11-12","conditions":"Obesity","enrollment":64},{"nctId":"NCT07061301","phase":"NA","title":"Transition to Hospital Discharge in Insulinized Patients With Type 2 Diabetes Mellitus","status":"RECRUITING","sponsor":"Instituto de Investigacion Sanitaria La Fe","startDate":"2024-08-01","conditions":"Type 2 Diabetes Mellitus (T2DM), Continuous Glucose Monitoring, CGM","enrollment":80},{"nctId":"NCT06334068","phase":"NA","title":"SHOrt-term Glycemic Control for Reducing Post-SURGical Complications","status":"COMPLETED","sponsor":"Mansoura University","startDate":"2024-05-08","conditions":"Diabetes, Uncontrolled Diabtetes","enrollment":53},{"nctId":"NCT06915428","phase":"NA","title":"Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities","status":"NOT_YET_RECRUITING","sponsor":"University of North Carolina, Chapel Hill","startDate":"2026-02-01","conditions":"Preterm Birth Complication, Preterm Birth, Preterm Birth Recurrence","enrollment":1228},{"nctId":"NCT07240012","phase":"NA","title":"Automated Insulin Delivery Versus Usual Insulin Treatment Modality Before and During Pregnancy in Women With Type 1 Diabetes","status":"RECRUITING","sponsor":"Rigshospitalet, Denmark","startDate":"2025-12-01","conditions":"Diabete Type 1, Pregnancy Complications","enrollment":305},{"nctId":"NCT07336914","phase":"NA","title":"Effect of Conventional vs Intensive Management on Gestational Diabetes and Maternal Fetal Outcomes","status":"RECRUITING","sponsor":"Khyber Medical University Peshawar","startDate":"2025-10-01","conditions":"Gestational Diabetes","enrollment":60},{"nctId":"NCT06463483","phase":"NA","title":"Automated Insulin Delivery in Adults With Advanced Kidney Disease","status":"RECRUITING","sponsor":"Imperial College London","startDate":"2025-11-01","conditions":"Chronic Kidney Diseases, Diabetes Mellitus","enrollment":12},{"nctId":"NCT05000021","phase":"NA","title":"Reducing Diabetes Distress Using Cognitive Behavioral Therapy in Young Adults With Type 1 Diabetes","status":"RECRUITING","sponsor":"Albert Einstein College of Medicine","startDate":"2022-06-27","conditions":"Type 1 Diabetes","enrollment":93},{"nctId":"NCT03999853","phase":"PHASE1, PHASE2","title":"Butyrate Adjuvant Therapy for Type 1 Diabetes","status":"COMPLETED","sponsor":"Mayo Clinic","startDate":"2022-07-28","conditions":"Type1diabetes","enrollment":6},{"nctId":"NCT05222815","phase":"NA","title":"Glucose Monitoring Comparison in Primary Care","status":"ACTIVE_NOT_RECRUITING","sponsor":"HealthPartners Institute","startDate":"2022-08-29","conditions":"Diabetes Mellitus, Type 2","enrollment":360},{"nctId":"NCT07314749","phase":"NA","title":"2025 Hypoglycemia Early-Warning and Physician-Nurse Collaborative Management Trial in Type 2 Diabetes","status":"COMPLETED","sponsor":"Third Affiliated Hospital, Sun Yat-Sen University","startDate":"2023-02-01","conditions":"Type 2 Diabetes Mellitus (T2DM)","enrollment":1255},{"nctId":"NCT07308925","phase":"NA","title":"Real-time Continuous Glucose Monitoring Compared With Intermittent Continuous Glucose Monitoring in People With Type 2 Diabetes Treated With Insulin.","status":"NOT_YET_RECRUITING","sponsor":"Hospital Universitario San Ignacio","startDate":"2026-01-31","conditions":"Type 2 Diabetes","enrollment":108},{"nctId":"NCT07282639","phase":"NA","title":"App-Based Certified Diabetes Education Therapy (AB-CDE)","status":"NOT_YET_RECRUITING","sponsor":"Oregon Health and Science University","startDate":"2026-01-15","conditions":"Type 1 Diabetes (T1D)","enrollment":99},{"nctId":"NCT03565770","phase":"NA","title":"Assessment of Individual Follow-up by Coaching Program for Type 1 Diabetes Children","status":"COMPLETED","sponsor":"University Hospital, Lille","startDate":"2018-09-29","conditions":"Diabetes type1","enrollment":106},{"nctId":"NCT05305794","phase":"PHASE3","title":"Effect of Weekly GLP1 Agonist Treatment in \"Double Diabetes\"","status":"RECRUITING","sponsor":"Centre Hospitalier Universitaire Dijon","startDate":"2022-07-12","conditions":"Double Diabetes","enrollment":76},{"nctId":"NCT07284511","phase":"PHASE2, PHASE3","title":"A Clinical Trial Using Tirzepatide to Help Adults With Type 1 Diabetes Automatically Control Their Blood Sugar","status":"NOT_YET_RECRUITING","sponsor":"Melissa-Rosina Pasqua","startDate":"2026-01-05","conditions":"Type 1 Diabetes, Type 1 Diabetes Mellitus, T1D","enrollment":105},{"nctId":"NCT07286500","phase":"","title":"\"Sexual Activity and Hypoglycemia Risk in Adults With Type 1 or Type 2 Diabetes Using Insulin Therapy and Continuous Glucose Monitoring\"","status":"RECRUITING","sponsor":"Medical University of Warsaw","startDate":"2025-07-30","conditions":"Type 1 Diabetes (T1D), Type 2 Diabetes (T2DM), Hypoglycemia","enrollment":100},{"nctId":"NCT07286019","phase":"NA","title":"Effects of Long Duration Cycling in People With Type 1 Diabetes","status":"ACTIVE_NOT_RECRUITING","sponsor":"Universitat de Girona","startDate":"2025-11-22","conditions":"Type 1 Diabetes (T1D)","enrollment":29},{"nctId":"NCT04510506","phase":"NA","title":"Artificial Pancreas - Adolescent Physiology & Psychology Longitudinal Evaluation","status":"COMPLETED","sponsor":"University of Virginia","startDate":"2020-11-19","conditions":"Type 1 Diabetes","enrollment":42},{"nctId":"NCT07265037","phase":"NA","title":"Integrated TCM - Western Medicine Strategy for Long - Distance Diabetes Management","status":"RECRUITING","sponsor":"Shanxi Bethune Hospital","startDate":"2025-11-01","conditions":"Diabetes Mellitus, Type 2, Integrated Traditional Chinese Medicine and Western Medicine, Telemedicine","enrollment":10000},{"nctId":"NCT06488469","phase":"NA","title":"Behavioural Problems and Cognition in Children With Hypoglycemia Unawareness in Type-1 Diabetes Mellitus","status":"NOT_YET_RECRUITING","sponsor":"University of Pittsburgh","startDate":"2026-07-01","conditions":"Type 1 Diabetes","enrollment":50},{"nctId":"NCT04225455","phase":"","title":"The Use of the Dexcom G6® in Commercial Pilots With Insulin-treated Diabetes","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Surrey","startDate":"2019-12-05","conditions":"Insulin Dependent Diabetes","enrollment":17},{"nctId":"NCT07234500","phase":"NA","title":"Evaluation of a Mobile Application Designed to Support Type 1 Diabetic Patients in Adjusting Their Insulin Doses.","status":"ENROLLING_BY_INVITATION","sponsor":"University of Baghdad","startDate":"2025-09-01","conditions":"Type One Diabetes Mellitus","enrollment":50},{"nctId":"NCT06418880","phase":"PHASE3","title":"Automated Insulin Delivery for Inpatients With Dysglycemia","status":"COMPLETED","sponsor":"Emory University","startDate":"2025-01-22","conditions":"Type 1 Diabetes, Type 2 Diabetes","enrollment":130},{"nctId":"NCT07063420","phase":"NA","title":"Patient Centered Multi-Agent Decision Support System (PCM-DSS) for Healthcare Providers","status":"RECRUITING","sponsor":"Daniel Chernavvsky, MD","startDate":"2025-10-28","conditions":"Type 2 Diabetes Treated With Insulin","enrollment":18},{"nctId":"NCT05933174","phase":"NA","title":"Promoting Alternatives to Sulfonylureas to Improve Patient Safety in Type 2 Diabetes","status":"RECRUITING","sponsor":"Ian J. Neeland, MD","startDate":"2023-10-01","conditions":"Type2diabetes","enrollment":220},{"nctId":"NCT05734313","phase":"NA","title":"Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression","status":"RECRUITING","sponsor":"Albert Einstein College of Medicine","startDate":"2023-03-31","conditions":"Diabetes, Type 1 Diabetes","enrollment":94},{"nctId":"NCT04016558","phase":"NA","title":"Behavioral Approaches to Reducing Diabetes Distress and Improving Glycemic Control","status":"COMPLETED","sponsor":"University of California, San Francisco","startDate":"2019-09-15","conditions":"Type 1 Diabetes, Diabetes Distress","enrollment":296},{"nctId":"NCT06411548","phase":"NA","title":"InsuLearn Feasibility With Type 1 Diabetes Patients Under MDI Therapy","status":"COMPLETED","sponsor":"University of Virginia","startDate":"2025-03-27","conditions":"Type 1 Diabetes Mellitus","enrollment":7},{"nctId":"NCT07201779","phase":"NA","title":"Adaptation of REDCHIP Intervention for the Portuguese Context","status":"NOT_YET_RECRUITING","sponsor":"ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida","startDate":"2026-04","conditions":"Type 1 Diabetes","enrollment":44},{"nctId":"NCT06974201","phase":"NA","title":"The Effect of Diabetes M Application Use Versus Conventional Bolus Calculation in Patients With Type 1 Diabetes Mellitus","status":"ACTIVE_NOT_RECRUITING","sponsor":"Medical University of Sofia","startDate":"2025-04-15","conditions":"Type 1 Diabetes Mellitus","enrollment":30},{"nctId":"NCT03617458","phase":"PHASE2","title":"Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension","status":"COMPLETED","sponsor":"Vanderbilt University Medical Center","startDate":"2018-08-23","conditions":"Pulmonary Artery Hypertension","enrollment":73},{"nctId":"NCT07039617","phase":"NA","title":"AIDANET At Home Study","status":"RECRUITING","sponsor":"Sue Brown","startDate":"2025-09-02","conditions":"Type 1 Diabetes","enrollment":40},{"nctId":"NCT05614089","phase":"PHASE4","title":"Human Versus Analogue Insulin for Youth With Type 1 Diabetes in Low-Resource Settings","status":"COMPLETED","sponsor":"Jing Luo","startDate":"2023-03-15","conditions":"Diabetes Mellitus, Type 1, Type 1 Diabetes","enrollment":400},{"nctId":"NCT06627517","phase":"NA","title":"Safety and Effectiveness of the Luna System in People With Type 1 Diabetes Mellitus","status":"ACTIVE_NOT_RECRUITING","sponsor":"Luna Diabetes","startDate":"2024-11-22","conditions":"Type 1 Diabetes Mellitus, Sleep Quality","enrollment":120},{"nctId":"NCT06167499","phase":"NA","title":"Therapeutic Education Consultations With Diabetic Patients Treated With Intensified Insulin Therapy","status":"TERMINATED","sponsor":"Hopital Nord Franche-Comte","startDate":"2024-02-09","conditions":"Diabete Mellitus, Insulin Dependent Diabetes","enrollment":7},{"nctId":"NCT07108426","phase":"NA","title":"Medical Education to Improve Diabetes Care and Outcomes in Hospitalized Patients","status":"COMPLETED","sponsor":"Catholic University of Pelotas","startDate":"2024-08-01","conditions":"Diabete Type 2, Hyperglycemic Therapy, Medical Education","enrollment":50},{"nctId":"NCT07094529","phase":"NA","title":"Personalized Hypoglycemia Outpatient Treatment - a Feasibility Study","status":"RECRUITING","sponsor":"Ottawa Hospital Research Institute","startDate":"2025-07-21","conditions":"Type 2 Diabetes (T2DM), Hypoglycemia (Diabetic)","enrollment":120},{"nctId":"NCT06180616","phase":"PHASE2","title":"Tirzepatide for the Treatment of Concurrent Type 1 Diabetes and Overweight or Obesity","status":"NOT_YET_RECRUITING","sponsor":"Royal North Shore Hospital","startDate":"2026-12","conditions":"Type 1 Diabetes Mellitus, Overweight and Obesity","enrollment":40},{"nctId":"NCT04621890","phase":"NA","title":"HCT Cash-Only INcentive to Promote Mealtime Insulin DOSE Engagement","status":"COMPLETED","sponsor":"Children's Mercy Hospital Kansas City","startDate":"2022-02-14","conditions":"Type 1 Diabetes","enrollment":39},{"nctId":"NCT02879409","phase":"NA","title":"HbA1c Variability in Type II Diabetes","status":"ACTIVE_NOT_RECRUITING","sponsor":"Weill Cornell Medical College in Qatar","startDate":"2016-11","conditions":"Diabetes Mellitus Type 2","enrollment":150},{"nctId":"NCT06984133","phase":"NA","title":"Structured Education Program and Glycemic Control in Adolescents With Type 1 Diabetes","status":"RECRUITING","sponsor":"Dasman Diabetes Institute","startDate":"2025-05-18","conditions":"Type 1 Diabetes (T1D), Type 1 Diabetes Mellitus (T1DM)","enrollment":128},{"nctId":"NCT04233229","phase":"NA","title":"Evaluation of a Closed-loop Insulin Delivery System at Home With Tailored Home Care Services in Poorly Controlled Type 2 Diabetes Patients (T2D)","status":"COMPLETED","sponsor":"Air Liquide Santé International","startDate":"2019-12-30","conditions":"Diabetes Type 2","enrollment":43},{"nctId":"NCT04809311","phase":"","title":"Remote Study Collecting Blood Glucose Values and Activity Data in Patients With Type 2 Diabetes on Different Treatments","status":"COMPLETED","sponsor":"Novo Nordisk A/S","startDate":"2024-04-30","conditions":"Diabetes Mellitus, Type 2","enrollment":156},{"nctId":"NCT04612933","phase":"NA","title":"Effectiveness of Video Consultations in Type 1 Diabetes Patients Treated With Insulin Pumps in the Outpatient Clinic","status":"COMPLETED","sponsor":"University of Southern Denmark","startDate":"2021-06-28","conditions":"Telemedicine, Insulin Dependent Diabetes Mellitus 1","enrollment":76},{"nctId":"NCT06850129","phase":"NA","title":"Efficacy of a Digital Educational Intervention in Patients With Type 2 Diabetes Mellitus","status":"COMPLETED","sponsor":"HOSPITAL VITHAS SEVILLA","startDate":"2020-10-26","conditions":"Diabetes Mellitus Type 2","enrollment":85},{"nctId":"NCT03652389","phase":"NA","title":"i-Matter: Investigating an mHealth Texting Tool for Embedding Patient-reported Data Into Diabetes Management","status":"COMPLETED","sponsor":"NYU Langone Health","startDate":"2018-12-18","conditions":"Type2 Diabetes","enrollment":246},{"nctId":"NCT05205928","phase":"PHASE2, PHASE3","title":"Weekly Subcutaneous Semaglutide as Adjunct to Closed-loop Therapy in Type 1 Diabetes Care","status":"COMPLETED","sponsor":"McGill University Health Centre/Research Institute of the McGill University Health Centre","startDate":"2022-10-02","conditions":"Type 1 Diabetes, Diabetes Mellitus, Type 1","enrollment":28},{"nctId":"NCT04252482","phase":"NA","title":"Validation of Sleep Healthcare System","status":"COMPLETED","sponsor":"National Taiwan University Hospital","startDate":"2020-02-07","conditions":"Obstructive Sleep Apnea","enrollment":52},{"nctId":"NCT05653050","phase":"NA","title":"Closing the Loop in People with Type 1 Diabetes","status":"COMPLETED","sponsor":"University of Cambridge","startDate":"2023-02-20","conditions":"Type 1 Diabetes","enrollment":26},{"nctId":"NCT03029702","phase":"PHASE4","title":"Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus","status":"COMPLETED","sponsor":"Maisa N. Feghali, MD","startDate":"2018-02-28","conditions":"Gestational Diabetes, Diabetes, Gestational, Pregnancy in Diabetes","enrollment":54},{"nctId":"NCT06435598","phase":"NA","title":"Tittle: Effect of Video-Based Health Education Intervention on Insulin Therapy Among Adults With Diabetes Mellitus in Dhulikhel Hospital","status":"RECRUITING","sponsor":"Kathmandu University School of Medical Sciences","startDate":"2024-06-01","conditions":"Knowledge on Insulin Therapy, Practice on Insulin Administration","enrollment":126},{"nctId":"NCT03660189","phase":"NA","title":"Two Bag System for Diabetic Ketoacidosis","status":"TERMINATED","sponsor":"MetroHealth Medical Center","startDate":"2018-09-17","conditions":"Diabetic Ketoacidosis","enrollment":57},{"nctId":"NCT00607945","phase":"PHASE1","title":"Dietary Fatty Acids As Complementary Therapy in Type 2 Diabetes Mellitus","status":"COMPLETED","sponsor":"Ohio State University","startDate":"2008-01","conditions":"Type 2 Diabetes Mellitus","enrollment":48},{"nctId":"NCT06650943","phase":"NA","title":"Nursing Intervention in Weight and Metabolic Syndrome Management in First-episode Psychosis (MetaKOP)","status":"RECRUITING","sponsor":"Hospital de Basurto","startDate":"2023-10-25","conditions":"First Episode Psychosis (FEP), Metabolic Syndrome X","enrollment":88},{"nctId":"NCT05760339","phase":"NA","title":"Intermittent Fasting Versus Carbohydrate Drinks Before Surgery","status":"RECRUITING","sponsor":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","startDate":"2023-03-20","conditions":"Perioperative Care, Intermittent Fasting, Carbohydrate Loading","enrollment":75},{"nctId":"NCT06119204","phase":"NA","title":"SAFE-LCD Trial, for Insulin-treated Adults Living With Type 2 Diabetes","status":"TERMINATED","sponsor":"Oviva UK Ltd","startDate":"2024-01-26","conditions":"Type 2 Diabetes Treated With Insulin, Diet Habit","enrollment":21},{"nctId":"NCT06587438","phase":"NA","title":"Effect of CGM on Glucose Control in Non-insulin-treated Patients with Type 2 Diabetes Mellitus","status":"NOT_YET_RECRUITING","sponsor":"Sinocare","startDate":"2024-10-15","conditions":"Diabetes Mellitus","enrollment":160},{"nctId":"NCT05904743","phase":"PHASE4","title":"INHALE-3: Afrezza® Combined With Insulin Degludec Versus Usual Care in Adults With Type 1 Diabetes","status":"COMPLETED","sponsor":"Mannkind Corporation","startDate":"2023-07-07","conditions":"Diabetes Mellitus, Type 1","enrollment":141},{"nctId":"NCT02558491","phase":"NA","title":"Feasibility of a Decision Support System to Reduce Glucose Variability in Subject With T1DM","status":"COMPLETED","sponsor":"Daniel Chernavvsky, MD","startDate":"2015-09","conditions":"Type 1 Diabetes Mellitus","enrollment":33},{"nctId":"NCT06449235","phase":"PHASE4","title":"Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh","status":"NOT_YET_RECRUITING","sponsor":"Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders","startDate":"2024-09","conditions":"Type2diabetes","enrollment":938},{"nctId":"NCT03380546","phase":"PHASE3","title":"Acarbose and Prandial Insulin for the Treatment of Gestational Diabetes Mellitus.","status":"TERMINATED","sponsor":"Assistance Publique - Hôpitaux de Paris","startDate":"2018-07-04","conditions":"Gestational Diabetes Mellitus in Pregnancy","enrollment":341},{"nctId":"NCT05458167","phase":"NA","title":"HEdia eXercise Algorithm - HEXA Study.","status":"COMPLETED","sponsor":"Hedia ApS","startDate":"2023-04-03","conditions":"Diabetes","enrollment":20},{"nctId":"NCT01939834","phase":"NA","title":"Early Feasibility Study of Adaptive Advisory/Automated (AAA) Control of Type 1 Diabetes","status":"TERMINATED","sponsor":"Sue Brown","startDate":"2013-12","conditions":"Type 1 Diabetes Mellitus","enrollment":10},{"nctId":"NCT04123054","phase":"NA","title":"A Novel mHealth Application Guided by an Optimization Algorithm for T1D Sensor-Augmented Insulin Injection Users","status":"COMPLETED","sponsor":"McGill University","startDate":"2020-03-05","conditions":"Diabetes Mellitus, Diabetes Mellitus, Type 1","enrollment":84},{"nctId":"NCT05553275","phase":"NA","title":"Permissive Intrapartum Glucose Control","status":"COMPLETED","sponsor":"The University of Texas Health Science Center, Houston","startDate":"2022-10-05","conditions":"Gestational Diabetes, Pregestational Diabetes","enrollment":96},{"nctId":"NCT06145360","phase":"PHASE4","title":"Evaluating the Efficacy and Safety of Empagliflozin Addition to Insulin and Oral Antidiabetic Medication (OAD) Regimen in Poorly Controlled Type 2 Diabetes and Obese Patient","status":"COMPLETED","sponsor":"SINA Health Education and Welfare Trust","startDate":"2023-12-01","conditions":"Glucose Metabolism Disorders, Diabetes Mellitus, Type 2, Hypoglycemic Agents","enrollment":150},{"nctId":"NCT04298229","phase":"PHASE3","title":"Efficacy and Safety of Dapagliflozin in Acute Heart Failure","status":"COMPLETED","sponsor":"Vanderbilt University Medical Center","startDate":"2020-04-01","conditions":"Heart Failure, Diabetes Mellitus, Type 2","enrollment":240},{"nctId":"NCT06297980","phase":"NA","title":"Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes","status":"RECRUITING","sponsor":"University of Colorado, Denver","startDate":"2024-03-15","conditions":"Type 1 Diabetes, Hypoglycemia, Hyperglycaemia Due to Type 1 Diabetes Mellitus","enrollment":150},{"nctId":"NCT04678661","phase":"NA","title":"My Dose Coach Mobile App to Support Insulin Titration and Maintenance","status":"TERMINATED","sponsor":"Linda Siminerio","startDate":"2021-02-15","conditions":"Diabetes Mellitus Type 2 - Insulin-Treated","enrollment":60},{"nctId":"NCT05580263","phase":"NA","title":"Different Order of Concurrent Training on Improving Visceral Adipose Tissue and Insulin Resistance.","status":"COMPLETED","sponsor":"National Tainan Junior College of Nursing","startDate":"2022-10-31","conditions":"Fat Burn, Aerobic Exercise, Resistance Exercise","enrollment":92},{"nctId":"NCT02496156","phase":"NA","title":"Shared Medical Decision Making in Pediatric Diabetes","status":"COMPLETED","sponsor":"Nemours Children's Clinic","startDate":"2015-02","conditions":"Type 1 Diabetes Mellitus","enrollment":153},{"nctId":"NCT04981808","phase":"NA","title":"Diabetes teleMonitoring of Patients in Insulin Therapy","status":"COMPLETED","sponsor":"Aalborg University Hospital","startDate":"2021-08-18","conditions":"Type 2 Diabetes Treated With Insulin","enrollment":331},{"nctId":"NCT04977908","phase":"NA","title":"Closing the Loop in Adults With Type 1 Diabetes (CLEAR)","status":"COMPLETED","sponsor":"University of Cambridge","startDate":"2021-08-31","conditions":"Type 1 Diabetes","enrollment":26},{"nctId":"NCT04914910","phase":"NA","title":"The Steno 780G Study","status":"COMPLETED","sponsor":"Steno Diabetes Center Copenhagen","startDate":"2021-06-08","conditions":"Type 1 Diabetes","enrollment":40},{"nctId":"NCT05369871","phase":"NA","title":"Evaluation of a Closed-loop System for the Treatment of Type 2 Diabetes at Home (DT2_2)","status":"COMPLETED","sponsor":"Diabeloop","startDate":"2022-08-29","conditions":"Diabetes Mellitus Type 2 - Insulin-Treated","enrollment":20},{"nctId":"NCT03945656","phase":"PHASE1","title":"A Research Study of How Overdosing of a New Once Weekly Medicine NNC0148-0287 C (Insulin 287) Influences the Blood Sugar Level in People With Type 2 Diabetes","status":"COMPLETED","sponsor":"Novo Nordisk A/S","startDate":"2019-05-07","conditions":"Diabetes Mellitus, Type 2","enrollment":43},{"nctId":"NCT05543850","phase":"NA","title":"Portable Artificial Pancreas Applied for Youth and Adolescents","status":"COMPLETED","sponsor":"Inreda Diabetic B.V.","startDate":"2022-10-28","conditions":"Diabetes Mellitus, Type 1","enrollment":20}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":6,"recentPublications":[{"date":"2001 Feb","pmid":"15635851","title":"[Short-term and long-term effect of metformin in type 1 diabetics].","journal":"Vnitrni lekarstvi"},{"date":"2001 Jan","pmid":"11137181","title":"Effect of octreotide on insulin requirement, hepatic glucose production, growth hormone, glucagon and c-peptide levels in type 2 diabetic patients with chronic renal failure or normal renal function.","journal":"Diabetes research and clinical practice"},{"date":"1989 Feb","pmid":"2918051","title":"Chronic treatment with pirenzepine decreases growth hormone secretion in insulin-dependent diabetes mellitus.","journal":"The Journal of clinical endocrinology and metabolism"},{"date":"1988 Jun","pmid":"3042316","title":"Salivary insulin in normal and type I diabetic subjects.","journal":"Diabetes care"},{"date":"1979 May-Jun","pmid":"510117","title":"Use of an artificial pancreas as a tool to determine subcutaneous insulin doses in juvenile diabetes.","journal":"Diabetes care"}],"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Usual insulin treatment","genericName":"Usual insulin treatment","companyName":"Centre Hospitalier Universitaire Dijon","companyId":"centre-hospitalier-universitaire-dijon","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Insulin works by stimulating glucose uptake in cells, thereby lowering blood glucose levels. Used for Type 1 diabetes, Type 2 diabetes.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}