{"id":"us-licensed-epoetin-alfa","safety":{"commonSideEffects":[{"rate":"2-5%","effect":"Thromboembolism"},{"rate":"10-20%","effect":"Hypertension"},{"rate":"10-20%","effect":"Headache"},{"rate":"10-20%","effect":"Fatigue"},{"rate":"10-20%","effect":"Nausea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This results in an increase in red blood cell production, which can help alleviate anemia in patients with chronic kidney disease or those undergoing chemotherapy. Epoetin alfa is a recombinant form of human erythropoietin, a hormone that plays a crucial role in regulating red blood cell production.","oneSentence":"Epoetin alfa stimulates erythropoiesis by binding to the erythropoietin receptor.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:53:20.033Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Anemia associated with chronic kidney disease"},{"name":"Anemia associated with chemotherapy"}]},"trialDetails":[{"nctId":"NCT01693029","phase":"PHASE3","title":"Study to Compare Safety and Efficacy of HX575 Epoetin Alfa and US-licensed Epoetin Alfa","status":"COMPLETED","sponsor":"Sandoz","startDate":"2012-09","conditions":"Anemia, Chronic Kidney Disease (CKD)","enrollment":435}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":3,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Epogen®","Procrit®"],"phase":"phase_3","status":"active","brandName":"US-licensed epoetin alfa","genericName":"US-licensed epoetin alfa","companyName":"Sandoz","companyId":"sandoz","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Epoetin alfa stimulates erythropoiesis by binding to the erythropoietin receptor. Used for Anemia associated with chronic kidney disease, Anemia associated with chemotherapy.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}