{"id":"upa-ecx2","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL217327","moleculeType":"Protein","molecularWeight":"1153.36"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"UPA is a serine protease involved in plasminogen activation, fibrin degradation, and cell migration. By inhibiting uPA activity, UPA-ECx2 may reduce pathological fibrinolysis and cellular invasion. The ECx2 designation suggests an engineered or conjugated formulation, though specific structural details are limited in public literature.","oneSentence":"UPA-ECx2 is an uPA (urokinase plasminogen activator) inhibitor conjugate designed to target and inhibit fibrinolysis and cell migration pathways.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:37:32.031Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[]},"trialDetails":[{"nctId":"NCT02859337","phase":"PHASE4","title":"Effectiveness of Orally Dosed Emergency Contraception in Obese Women - UPA","status":"COMPLETED","sponsor":"Oregon Health and Science University","startDate":"2017-05-30","conditions":"Obesity, Contraception","enrollment":64}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["ella","ella-one"],"phase":"marketed","status":"active","brandName":"UPA-ECx2","genericName":"UPA-ECx2","companyName":"Oregon Health and Science University","companyId":"oregon-health-and-science-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":1},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}