{"id":"tv-p2-vp8","safety":{"commonSideEffects":[{"rate":"null","effect":"Injection site pain"}]},"_chembl":{"chemblId":"CHEMBL4108679","moleculeType":"Small molecule","molecularWeight":"520.73"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"TV P2-VP8 is a vaccine candidate that aims to provide protection against a specific disease. The exact mechanism of action is not publicly available.","oneSentence":"TV P2-VP8 is a vaccine candidate.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:51:14.146Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"COVID-19"}]},"trialDetails":[{"nctId":"NCT04344054","phase":"PHASE2","title":"Mixed Schedule Study of Live Oral Rotavirus Vaccines and Trivalent P2-VP8 Subunit Rotavirus Vaccine","status":"COMPLETED","sponsor":"PATH","startDate":"2021-02-22","conditions":"Rotavirus Vaccine","enrollment":850},{"nctId":"NCT04010448","phase":"PHASE3","title":"A Trial to Assess the Safety, Immunogenicity and Efficacy of a Trivalent Rotavirus P2-VP8 Subunit Vaccine in Prevention of Severe Rotavirus Gastroenteritis in Healthy Infants in Africa and India","status":"UNKNOWN","sponsor":"PATH","startDate":"2019-10-10","conditions":"Rotavirus Infection of Children","enrollment":8200}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"TV P2-VP8","genericName":"TV P2-VP8","companyName":"PATH","companyId":"path","modality":"Biologic","firstApprovalDate":"","aiSummary":"Trivalent P2-VP8 is a small molecule subunit rotavirus vaccine. It is being studied in a Phase II clinical trial for its immunogenicity and safety in combination with Rotarix and RV3-BB in preventing rotavirus infection in children.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}