{"id":"trivalent-rotavirus-genetic-reassortment-vaccine","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Fever"},{"rate":"5-10%","effect":"Vomiting"},{"rate":"5-10%","effect":"Diarrhea"},{"rate":"5-10%","effect":"Injection site pain"}]},"_chembl":{"chemblId":"CHEMBL2108573","moleculeType":"Vaccine component"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"The trivalent rotavirus genetic reassortment vaccine works by introducing inactivated rotavirus antigens to stimulate an immune response, providing protection against severe rotavirus gastroenteritis. This is achieved through the genetic reassortment of rotavirus strains, which allows for the creation of a vaccine that can induce immunity against multiple serotypes of the virus.","oneSentence":"This vaccine induces immunity against rotavirus by introducing inactivated rotavirus antigens.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:40:11.602Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of severe rotavirus gastroenteritis in infants and young children"}]},"trialDetails":[{"nctId":"NCT01738074","phase":"PHASE3","title":"Phase Three Clinical Trials of Trivalent Rotavirus Genetic Reassortment Vaccine","status":"UNKNOWN","sponsor":"Center for Disease Control and Prevention, Henan Province","startDate":"2012-08","conditions":"Randomized, Double-blind, Placebo Control Design","enrollment":10020}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"trivalent rotavirus genetic reassortment vaccine","genericName":"trivalent rotavirus genetic reassortment vaccine","companyName":"Center for Disease Control and Prevention, Henan Province","companyId":"center-for-disease-control-and-prevention-henan-province","modality":"Biologic","firstApprovalDate":"","aiSummary":"This vaccine induces immunity against rotavirus by introducing inactivated rotavirus antigens. Used for Prevention of severe rotavirus gastroenteritis in infants and young children.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}