{"id":"trimethidinium-methosulfate","rwe":[{"pmid":"13859541","year":"1962","title":"Acute systemic and coronary hemodynamic effects of trimethidinium methosulfate.","finding":"","journal":"Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)","studyType":"Clinical Study"},{"pmid":"14476712","year":"1962","title":"A controlled clinical comparison of guanethidine and trimethidinium methosulfate.","finding":"","journal":"Journal of the Germantown Hospital","studyType":"Clinical Study"},{"pmid":"13856236","year":"1960","title":"Trimethidinium methosulfate in the treatment of moderate and severe hypertension.","finding":"","journal":"Journal of the American Geriatrics Society","studyType":"Clinical Study"},{"pmid":"14431862","year":"1960","title":"The treatment of hypertension with trimethidinium methosulfate in an outpatient clinic group.","finding":"","journal":"Southern medical journal","studyType":"Clinical Study"},{"pmid":"13802828","year":"1959","title":"Use of trimethidinium methosulfate (a new ganglionic blocking agent) in the treatment of hypertension.","finding":"","journal":"Annals of internal medicine","studyType":"Clinical Study"}],"tags":[{"label":"trimethidinium","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"camphonium","offLabel":[],"synonyms":["trimethidinium diiodide","camphonium","trimethidinium","trimethidinium methosulfate"],"timeline":[],"brandName":"Camphonium","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"trimethidinium","explanation":"Imagine your body's cells are like locks, and Camphonium is a key that fits into one of those locks. When it binds to the lock, it can affect how the cell works, but we don't yet know exactly how it does that or what it does to the cell. More research is needed to understand how Camphonium works and what it does in the body.","oneSentence":"Camphonium works by interacting with a specific target in the body, although its exact mechanism of action is currently unknown.","technicalDetail":"Camphonium is a quaternary ammonium compound that acts as a cholinergic antagonist, potentially affecting the parasympathetic nervous system, but its precise mechanism of action and pharmacokinetics are unknown."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3845","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=TRIMETHIDINIUM METHOSULFATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T02:42:47.773283","biosimilars":[],"competitors":[],"genericName":"trimethidinium methosulfate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"FZ7142TV3J","CHEBI":"CHEBI:135103","INN_ID":"808","UMLSCUI":"C0077159","ChEMBL_ID":"CHEMBL1708232","PUBCHEM_CID":"26484","SNOMEDCT_US":"47414005","SECONDARY_CAS_RN":"14149-43-0","MESH_SUPPLEMENTAL_RECORD_UI":"C034340"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":7,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1962 May","pmid":"13859541","title":"Acute systemic and coronary hemodynamic effects of trimethidinium methosulfate.","journal":"Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)"},{"date":"1962 Feb","pmid":"14476712","title":"A controlled clinical comparison of guanethidine and trimethidinium methosulfate.","journal":"Journal of the Germantown Hospital"},{"date":"1960 Mar","pmid":"13856236","title":"Trimethidinium methosulfate in the treatment of moderate and severe hypertension.","journal":"Journal of the American Geriatrics Society"},{"date":"1960 Feb","pmid":"14431862","title":"The treatment of hypertension with trimethidinium methosulfate in an outpatient clinic group.","journal":"Southern medical journal"},{"date":"1959 Nov","pmid":"13802828","title":"Use of trimethidinium methosulfate (a new ganglionic blocking agent) in the treatment of hypertension.","journal":"Annals of internal medicine"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Camphonium is a small molecule with the synonyms METHOSULFATE DE TRIMETHIDINIUM, METOSULFATO DE TRIMETIDINIO, and TRIMETHIDINIUM METHOSULFATE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}