{"id":"triamcinolone-betamethason","safety":{"commonSideEffects":[{"rate":"null","effect":"Cushing's syndrome"},{"rate":"null","effect":"Glucocorticoid-induced osteoporosis"},{"rate":"null","effect":"Increased risk of infections"},{"rate":"null","effect":"Hypertension"}]},"_chembl":{"chemblId":"CHEMBL1200449","moleculeType":"Small molecule","molecularWeight":"478.51"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"They work by binding to glucocorticoid receptors, which then translocate to the nucleus and inhibit the transcription of pro-inflammatory genes. This leads to a decrease in the production of inflammatory cytokines and other mediators, resulting in anti-inflammatory and immunosuppressive effects.","oneSentence":"Triamcinolone and betamethasone are synthetic glucocorticoids that inhibit the release of inflammatory mediators.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:40:02.238Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Severe asthma attacks"},{"name":"Severe allergic reactions (anaphylaxis)"},{"name":"Severe skin conditions (e.g. psoriasis, eczema)"},{"name":"Severe inflammatory conditions (e.g. rheumatoid arthritis, lupus)"}]},"trialDetails":[{"nctId":"NCT03958344","phase":"PHASE3","title":"Intraorbital Injection Versus Oral Steroid in Anterior Idiopathic Orbital Inflammation","status":"UNKNOWN","sponsor":"Iran University of Medical Sciences","startDate":"2022-01-01","conditions":"Orbital Pseudotumor","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Injectable Steroid"],"phase":"phase_3","status":"active","brandName":"Triamcinolone + Betamethason","genericName":"Triamcinolone + Betamethason","companyName":"Iran University of Medical Sciences","companyId":"iran-university-of-medical-sciences","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Triamcinolone and betamethasone are synthetic glucocorticoids that inhibit the release of inflammatory mediators. Used for Severe asthma attacks, Severe allergic reactions (anaphylaxis), Severe skin conditions (e.g. psoriasis, eczema).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}