{"id":"treatment-in-cavitary-pulmonary-aspergillosis","safety":{"commonSideEffects":[{"rate":null,"effect":"Hepatotoxicity"},{"rate":null,"effect":"Nephrotoxicity"},{"rate":null,"effect":"Gastrointestinal disturbances"},{"rate":null,"effect":"Infusion-related reactions"}]},"_chembl":{"chemblId":"CHEMBL5715933","moleculeType":null,"molecularWeight":"612.41"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Cavitary pulmonary aspergillosis is a chronic fungal infection of the lungs caused by Aspergillus species, often requiring combination antifungal therapy. Treatment typically involves azoles (such as itraconazole or voriconazole) as first-line agents, sometimes combined with amphotericin B or other antifungals, and may include surgical intervention for large cavitary lesions. The specific drug formulation from PGIMER is not publicly detailed in standard pharmaceutical databases.","oneSentence":"This is a treatment regimen for cavitary pulmonary aspergillosis, likely combining antifungal agents to eliminate Aspergillus fungal infection in lung cavities.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:14:07.127Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cavitary pulmonary aspergillosis"}]},"trialDetails":[{"nctId":"NCT01259336","phase":"PHASE4","title":"Efficacy Of Itraconazole In Chronic Cavitary Pulmonary Aspergillosis","status":"COMPLETED","sponsor":"Post Graduate Institute of Medical Education and Research, Chandigarh","startDate":"2010-07","conditions":"Chronic Cavitary Pulmonary Aspergillosis","enrollment":31}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":70,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"treatment in cavitary pulmonary aspergillosis","genericName":"treatment in cavitary pulmonary aspergillosis","companyName":"Post Graduate Institute of Medical Education and Research, Chandigarh","companyId":"post-graduate-institute-of-medical-education-and-research-chandigarh","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This is a treatment regimen for cavitary pulmonary aspergillosis, likely combining antifungal agents to eliminate Aspergillus fungal infection in lung cavities. Used for Cavitary pulmonary aspergillosis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}