{"id":"traumeel-zeel-injectable-solution","safety":{"commonSideEffects":[{"rate":null,"effect":"Local injection site reactions"},{"rate":null,"effect":"Allergic reactions to botanical components"},{"rate":null,"effect":"Mild systemic symptoms"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"These injectable solutions contain a blend of homeopathic dilutions of botanical extracts (arnica, calendula, hypericum, echinacea, and others) and mineral compounds intended to reduce inflammation, promote tissue repair, and support immune function. The exact molecular mechanisms are not well-characterized by conventional pharmacology, as these are traditional homeopathic formulations used in integrative medicine for musculoskeletal and degenerative conditions.","oneSentence":"Traumeel and Zeel are homeopathic combination remedies that modulate inflammatory and immune responses through multiple plant and mineral constituents.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:39:53.223Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Traumatic injuries, contusions, and musculoskeletal trauma (Traumeel)"},{"name":"Degenerative joint disease and osteoarthritis (Zeel)"},{"name":"Rheumatoid arthritis and inflammatory joint conditions"}]},"trialDetails":[{"nctId":"NCT01887678","phase":"PHASE3","title":"Study of Intra-articular Injections vs Placebo in Patients With Pain From Osteoarthritis of the Knee","status":"COMPLETED","sponsor":"Biologische Heilmittel Heel GmbH","startDate":"2013-06","conditions":"Osteoarthritis, Knee","enrollment":287}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Traumeel","Zeel"],"phase":"phase_3","status":"active","brandName":"Traumeel® / Zeel® Injectable Solution","genericName":"Traumeel® / Zeel® Injectable Solution","companyName":"Biologische Heilmittel Heel GmbH","companyId":"biologische-heilmittel-heel-gmbh","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Traumeel/Zeel Injectable Solution is a treatment that has been studied in clinical trials for osteoarthritis of the knee. It has been tested in a multi-center, double-blind, randomized controlled trial as an intra-articular injection compared to a placebo.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}