{"id":"transdermal-delivery-system","_chembl":null,"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=Transdermal delivery system","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T06:49:50.480877+00:00"},"aiSummary":{"url":"","method":"ai_extraction","source":"AI Strategic Summary","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"ai_extraction","retrievedAt":"2026-04-20T06:50:13.127263+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T06:49:57.264347+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=Transdermal delivery system","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T06:49:57.881607+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL2108729/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-20T06:49:59.083927+00:00"}},"_dailymed":{"setId":"21679c9c-27d7-47c9-828e-b4cc405816cc","title":"NITROGLYCERIN TRANSDERMAL DELIVERY SYSTEM (NITROGLYCERIN) PATCH [PHYSICIANS TOTAL CARE, INC.]"},"aiSummary":"Mundipharma AB's transdermal delivery system is currently on the market, leveraging a unique mechanism to address its primary indication. The key composition patent is set to expire in 2028, providing a significant period of market exclusivity and potential revenue protection. However, the lack of specified competitors and trial results poses a strategic risk, as it may be challenging to assess the drug's competitive landscape and efficacy compared to emerging alternatives.","_scrapedAt":"2026-03-28T00:13:41.854Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_validation":{"fieldsValidated":1,"lastValidatedAt":"2026-04-20T06:50:13.127573+00:00","fieldsConflicting":0,"overallConfidence":0.95},"trialDetails":[{"nctId":"NCT05674240","phase":"","title":"Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain","status":"COMPLETED","sponsor":"Wake Forest University Health Sciences","startDate":"2022-12-06","conditions":"Cancer Pain, Chronic Pain, Cancer Associated Pain","enrollment":30},{"nctId":"NCT07452692","phase":"PHASE1","title":"A Study to Assess the Skin Irritation and Sensitization of Selegiline TDS in Healthy Subjects","status":"NOT_YET_RECRUITING","sponsor":"Corium Innovations, Inc.","startDate":"2026-07-01","conditions":"Major Depressive Disorder (MDD)","enrollment":230},{"nctId":"NCT06528665","phase":"","title":"Determine PK Profiles of Ozanimod and Its' Major Metabolites in Healthy Subjects","status":"COMPLETED","sponsor":"Corium Innovations, Inc.","startDate":"2025-02-10","conditions":"Multiple Sclerosis, Ulcerative Colitis","enrollment":24},{"nctId":"NCT07408440","phase":"NA","title":"Transdermal Testosterone Gel for Female Sexual Interest and Arousal Disorder in Peri- and Post Menopause","status":"NOT_YET_RECRUITING","sponsor":"The University of Texas Health Science Center, Houston","startDate":"2026-04-01","conditions":"Menopause, Sexual Dysfunction, Libido Disorder","enrollment":150},{"nctId":"NCT03904186","phase":"NA","title":"Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV","status":"COMPLETED","sponsor":"Massachusetts General Hospital","startDate":"2019-12-19","conditions":"Human Immunodeficiency Virus, Smoking Cessation, Smoking, Cigarette","enrollment":131},{"nctId":"NCT06502964","phase":"PHASE2","title":"Study of ALTO-101 in Patients With Schizophrenia","status":"RECRUITING","sponsor":"Alto Neuroscience","startDate":"2024-06-11","conditions":"Schizophrenia, Cognitive Impairment","enrollment":82},{"nctId":"NCT06161675","phase":"NA","title":"Feasibility of Delivering VergeRx at FQHCs","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Virginia","startDate":"2024-09-23","conditions":"Tobacco Use Cessation","enrollment":100},{"nctId":"NCT05660525","phase":"NA","title":"Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia","status":"RECRUITING","sponsor":"University of Virginia","startDate":"2024-03-06","conditions":"Smoking Cessation, Smoking, Cigarette, Smoking Reduction","enrollment":768},{"nctId":"NCT04009044","phase":"PHASE2","title":"Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast","status":"ACTIVE_NOT_RECRUITING","sponsor":"Northwestern University","startDate":"2020-02-17","conditions":"Cancer Survivor, Ductal Breast Carcinoma In Situ, Invasive Breast Carcinoma","enrollment":156},{"nctId":"NCT07208890","phase":"NA","title":"Methotrexate Iontophoresis Versus Methotrexate 1% Gel on Depigmentation in Vitiligo Patients","status":"NOT_YET_RECRUITING","sponsor":"Pharos University in Alexandria","startDate":"2025-11-10","conditions":"Vitiligo - Evaluation of Methotrexate Iontophoresis and Topical Methotrexate Gel as Localized Treatment Approache","enrollment":30},{"nctId":"NCT05882812","phase":"PHASE2","title":"Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to Osteoarthritis","status":"COMPLETED","sponsor":"ZetrOZ, Inc.","startDate":"2023-06-03","conditions":"Osteo Arthritis Knee, Arthritis","enrollment":200},{"nctId":"NCT06948058","phase":"NA","title":"Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy","status":"RECRUITING","sponsor":"Brown University","startDate":"2025-04-01","conditions":"Smoking Cessation, Obesity and Obesity-related Medical Conditions","enrollment":60},{"nctId":"NCT06257537","phase":"PHASE2","title":"Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis","status":"RECRUITING","sponsor":"ZetrOZ, Inc.","startDate":"2024-10-01","conditions":"Osteo Arthritis Knee, Arthritis","enrollment":300},{"nctId":"NCT05883241","phase":"PHASE1","title":"Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture","status":"RECRUITING","sponsor":"ZetrOZ, Inc.","startDate":"2023-06-01","conditions":"Bone Fracture, Fresh Fracture","enrollment":90},{"nctId":"NCT05139121","phase":"PHASE3","title":"Study of the Safety and Efficacy of MR-100A-01 in Approximately 1200 Healthy Women for up to 13 Cycles","status":"COMPLETED","sponsor":"Mylan Technologies Inc.","startDate":"2021-10-26","conditions":"Contraception","enrollment":1319},{"nctId":"NCT06738732","phase":"PHASE1, PHASE2","title":"CBD Delivery with the A-Synaptic GT4 Transdermal Delivery System in with Dravet Syndrome And/or Lennox-Gastaut Syndrome","status":"NOT_YET_RECRUITING","sponsor":"Alexander Rotenberg","startDate":"2025-01","conditions":"Lennox-Gastaut Syndrome (LGS), Dravet Syndrome (DS)","enrollment":25},{"nctId":"NCT04617782","phase":"PHASE1","title":"Pharmacokinetic Study of 5 and 10 mg Corplex™ Donepezil TDS Compared to 10 mg Aricept® in Healthy Volunteers","status":"COMPLETED","sponsor":"Corium, Inc.","startDate":"2020-12-08","conditions":"Healthy Subjects","enrollment":60},{"nctId":"NCT00273468","phase":"PHASE3","title":"To Study the Safety and Effectiveness of a Granisetron Patch to Treat Chemotherapy-Induced Nausea and Vomiting (CINV)","status":"COMPLETED","sponsor":"Kyowa Kirin Co., Ltd.","startDate":"2006-01","conditions":"Chemotherapy-induced Nausea and Vomiting","enrollment":630},{"nctId":"NCT05525078","phase":"NA","title":"Quit or Switch: E-cigarette Study","status":"COMPLETED","sponsor":"Medical University of South Carolina","startDate":"2022-08-01","conditions":"Tobacco Use","enrollment":30},{"nctId":"NCT00648414","phase":"PHASE1","title":"Study of the Effect of Clinical Procedures on Drug Delivery of Mylan Fentanyl Transdermal System 25 µg/hr and Duragesic® 25 µg/hr","status":"TERMINATED","sponsor":"Mylan Pharmaceuticals Inc","startDate":"2006-10","conditions":"Healthy","enrollment":12},{"nctId":"NCT06063421","phase":"NA","title":"Comparison of Nicotine Replacement Therapy and Electronic Cigarettes for Smoking Cessation in Pakistan","status":"NOT_YET_RECRUITING","sponsor":"Strategic Health Research Limited","startDate":"2024-06-01","conditions":"Smoking Cessation, Electronic Cigarette Use","enrollment":438},{"nctId":"NCT01711021","phase":"PHASE2","title":"Study to Evaluate Safety & Efficacy of d-Amphetamine Transdermal System vs Placebo in Children & Adolescents With ADHD","status":"COMPLETED","sponsor":"Noven Pharmaceuticals, Inc.","startDate":"2012-10","conditions":"Attention Deficit Hyperactivity Disorder","enrollment":110},{"nctId":"NCT04366726","phase":"PHASE1","title":"Study to Evaluate the Pharmacokinetics (PK), Pharmacodynamics (PD), and Usability of Abaloparatide-solid Microstructured Transdermal System (sMTS) in Postmenopausal Women With Low Bone Mineral Density (BMD)","status":"COMPLETED","sponsor":"Radius Health, Inc.","startDate":"2019-04-09","conditions":"Postmenopausal Osteoporosis","enrollment":22},{"nctId":"NCT02138357","phase":"PHASE4","title":"Butrans for Treatment of Restless Legs Syndrome","status":"WITHDRAWN","sponsor":"Massachusetts General Hospital","startDate":"2014-04","conditions":"Restless Legs Syndrome","enrollment":""},{"nctId":"NCT04391842","phase":"PHASE1","title":"Sustained Acoustic Medicine (SAM) Combined With a Diclofenac Ultrasound Coupling Patch for Knee Osteoarthritis","status":"COMPLETED","sponsor":"ZetrOZ, Inc.","startDate":"2019-09-01","conditions":"Osteo Arthritis Knee, Arthritis","enrollment":34},{"nctId":"NCT04568980","phase":"","title":"Assessment of Contraceptive Safety and Effectiveness in Cystic Fibrosis","status":"COMPLETED","sponsor":"University of Washington","startDate":"2020-09-30","conditions":"Cystic Fibrosis, Contraception","enrollment":562},{"nctId":"NCT04732195","phase":"NA","title":"Pilocarpine Microneedles for Sweat Induction (PMN-SI)","status":"COMPLETED","sponsor":"Emory University","startDate":"2022-01-20","conditions":"Cystic Fibrosis","enrollment":50},{"nctId":"NCT05127746","phase":"PHASE1","title":"Phase 1 Clinical Trial of DA-5207 in Healthy Adults","status":"COMPLETED","sponsor":"Dong-A ST Co., Ltd.","startDate":"2021-11-25","conditions":"Healthy","enrollment":51},{"nctId":"NCT01937156","phase":"PHASE3","title":"A Randomized Controlled Trial of SP-01 (Granisetron Transdermal Delivery System) in Chemotherapy-induced Nausea and Vomiting","status":"COMPLETED","sponsor":"Solasia Pharma K.K.","startDate":"2013-08","conditions":"Chemotherapy-induced Nausea and Vomiting","enrollment":313},{"nctId":"NCT04064411","phase":"PHASE3","title":"Efficacy & Safety of Abaloparatide-Solid Microstructured Transdermal System in Postmenopausal Women With Osteoporosis","status":"COMPLETED","sponsor":"Radius Health, Inc.","startDate":"2019-08-05","conditions":"Postmenopausal Osteoporosis","enrollment":511},{"nctId":"NCT05649241","phase":"NA","title":"QuitAid Pilot Feasibility Trial","status":"COMPLETED","sponsor":"University of Virginia","startDate":"2021-08-31","conditions":"Smoking Cessation","enrollment":24},{"nctId":"NCT03229798","phase":"PHASE1","title":"Sofusa System With Sumatriptan (KC5010) Phase 1 Dose Escalation Safety and PK Study (KCC-SMT-002)","status":"COMPLETED","sponsor":"Sorrento Therapeutics, Inc.","startDate":"2018-01-17","conditions":"Migraine Disorders","enrollment":19},{"nctId":"NCT01096966","phase":"PHASE2","title":"Study of the Efficacy and Safety of Bupivacaine TTS Patch in Patients With Chronic Low Back Pain","status":"COMPLETED","sponsor":"Durect","startDate":"2010-03","conditions":"Chronic Low Back Pain","enrollment":263},{"nctId":"NCT04472143","phase":"PHASE2","title":"Granisetron Transdermal Patch for Prophylaxis of Nausea and Vomiting in Patients Receiving Oral Anticancer Agents","status":"UNKNOWN","sponsor":"Fudan University","startDate":"2020-07-18","conditions":"Chemotherapy-induced Nausea and Vomiting (CINV)","enrollment":60},{"nctId":"NCT03021083","phase":"PHASE4","title":"IONSYS Feasibility Study","status":"WITHDRAWN","sponsor":"Hospital for Special Surgery, New York","startDate":"2017-11-01","conditions":"Spinal Injury","enrollment":""},{"nctId":"NCT03205605","phase":"EARLY_PHASE1","title":"Effect of Heat on Oxybutynin Release and Absorption From Oxybutynin Products","status":"COMPLETED","sponsor":"University of Maryland, Baltimore","startDate":"2018-01-02","conditions":"Heat Effect","enrollment":13},{"nctId":"NCT03915626","phase":"EARLY_PHASE1","title":"Effect of Heat on Rivastigmine TDS Products","status":"COMPLETED","sponsor":"University of Maryland, Baltimore","startDate":"2019-10-04","conditions":"Bioavailability","enrollment":7},{"nctId":"NCT05187494","phase":"NA","title":"Enhancing the Efficiency of EMLA Cream in Palatal Anesthesia for Children","status":"COMPLETED","sponsor":"Damascus University","startDate":"2021-05-20","conditions":"Extrusion of Tooth","enrollment":75},{"nctId":"NCT04936984","phase":"PHASE1","title":"Study to Evaluate and Compare the Bioequivalence of Two Abaloparatide-sMTS Treatments in Healthy Women.","status":"COMPLETED","sponsor":"Radius Health, Inc.","startDate":"2020-11-16","conditions":"Osteoporosis","enrollment":36},{"nctId":"NCT04663464","phase":"PHASE1","title":"Study to Evaluate and Compare the PK Profiles of Abaloparatide-SC and Abaloparatide-sMTS in a Cohort of Healthy Men and Healthy Women.","status":"COMPLETED","sponsor":"Radius Health, Inc.","startDate":"2020-11-16","conditions":"Healthy Volunteers","enrollment":52},{"nctId":"NCT03859336","phase":"NA","title":"High-Frequency Transdermal Neuromodulation to Decrease Anxiety and Improve Sleep in ASD","status":"COMPLETED","sponsor":"Phoenix Children's Hospital","startDate":"2019-05-21","conditions":"Autism Spectrum Disorder","enrollment":10},{"nctId":"NCT00125983","phase":"PHASE2","title":"Drug Interactions Between Lopinavir/Ritonavir and Oral or Patch Contraceptives in HIV Infected Women","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"","conditions":"HIV Infections, Pregnancy","enrollment":32},{"nctId":"NCT04912271","phase":"PHASE3","title":"Granisetron Transdermal Patch for Prophylaxis of Delayed CINV","status":"UNKNOWN","sponsor":"Fudan University","startDate":"2021-06-10","conditions":"Chemotherapy-induced Nausea and Vomiting (CINV)","enrollment":140},{"nctId":"NCT04479865","phase":"PHASE1","title":"Phase 1 Clinical Trial to Evaluate the Safety, PK and PD of DA-5207 TDS in Healthy Adults","status":"UNKNOWN","sponsor":"Dong-A ST Co., Ltd.","startDate":"2020-07-28","conditions":"Healthy","enrollment":49},{"nctId":"NCT04013477","phase":"PHASE1","title":"Single-ascending Dose Phase 1 Clinical Trial to Evaluate the Safety and PK of DA-5207 TDS in Healthy Adults","status":"COMPLETED","sponsor":"Dong-A ST Co., Ltd.","startDate":"2019-06-18","conditions":"Healthy","enrollment":40},{"nctId":"NCT04534491","phase":"PHASE3","title":"Study to Gather Information About the Actual Use of an Adhesive Patch Placed on the Skin to Deliver Oxytrol Through the Skin Into the Bloodstream.","status":"COMPLETED","sponsor":"Bayer","startDate":"2010-05-25","conditions":"Overactive Bladder","enrollment":855},{"nctId":"NCT01771627","phase":"NA","title":"Varenicline or Nicotine Patch in Promoting Smoking Cessation Among Current Smokers","status":"COMPLETED","sponsor":"Roswell Park Cancer Institute","startDate":"2012-10-22","conditions":"Tobacco Use Disorder","enrollment":300},{"nctId":"NCT04517890","phase":"NA","title":"Transdermal Lidocaine Administration Prior to Insertion Levonorgestrel-releasing Intrauterine System","status":"UNKNOWN","sponsor":"Aswan University Hospital","startDate":"2020-09-01","conditions":"IUCD Complication","enrollment":200},{"nctId":"NCT04021420","phase":"PHASE1, PHASE2","title":"Safety and Efficacy of Sonocloud Device Combined With Nivolumab in Brain Metastases From Patients With Melanoma","status":"UNKNOWN","sponsor":"Assistance Publique - Hôpitaux de Paris","startDate":"2019-10-24","conditions":"Melanoma, Metastatic Melanoma","enrollment":21},{"nctId":"NCT01674621","phase":"PHASE2","title":"Phase 2 Study of BA058 (Abaloparatide) Transdermal Delivery in Postmenopausal Women With Osteoporosis","status":"COMPLETED","sponsor":"Radius Health, Inc.","startDate":"2012-09-25","conditions":"Post Menopausal Osteoporosis","enrollment":250},{"nctId":"NCT02158572","phase":"PHASE3","title":"Efficacy, Safety and Tolerability Study of Agile AG200-15 Transdermal Contraceptive Delivery System","status":"COMPLETED","sponsor":"Agile Therapeutics","startDate":"2014-08","conditions":"Healthy","enrollment":2032},{"nctId":"NCT01380353","phase":"EARLY_PHASE1","title":"Test Uniformity of Transdermal Drug Delivery to Breast Using Diclofenac Epolamine","status":"COMPLETED","sponsor":"Northwestern University","startDate":"2011-06","conditions":"Breast Cancer","enrollment":30},{"nctId":"NCT02312934","phase":"PHASE2","title":"Nicotinic Treatment of Post-Chemotherapy Subjective Cognitive Impairment: A Pilot Study","status":"COMPLETED","sponsor":"Vanderbilt University Medical Center","startDate":"2015-08","conditions":"Chemo Brain, Chemotherapy-related Cognitive Impairment, Chemo Fog","enrollment":22},{"nctId":"NCT02854540","phase":"NA","title":"Management of Palmar Hyperhidrosis With Hydrogel-based Iontophoresis","status":"COMPLETED","sponsor":"Stanford University","startDate":"2016-08","conditions":"Hyperhidrosis, Hyperhidrosis Palmaris et Plantaris","enrollment":13},{"nctId":"NCT03967964","phase":"PHASE1","title":"Pharmacokinetics of a Novel Vaginal Delivery System for Testosterone and Dehydroepiandrosterone (DHEA)","status":"COMPLETED","sponsor":"Laboratorios Andromaco S.A.","startDate":"2015-11-20","conditions":"Pharmacokinetics, Hormone Deficiency","enrollment":46},{"nctId":"NCT03721900","phase":"PHASE1","title":"Ketamine for Major Depressive Disorder","status":"UNKNOWN","sponsor":"Shenox Pharmaceuticals, LLC","startDate":"2018-12-28","conditions":"Major Depressive Disorder","enrollment":14},{"nctId":"NCT01422135","phase":"PHASE1","title":"Pharmacokinetic Study of AG200-15 Transdermal Patch to Three Anatomical Sites in Healthy Females","status":"COMPLETED","sponsor":"Agile Therapeutics","startDate":"2011-02","conditions":"Healthy","enrollment":24},{"nctId":"NCT01999114","phase":"PHASE1","title":"The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) at Doses up to 80 Micrograms/Hour (mcg/hr) and Naltrexone on Electrocardiogram (ECG) Intervals in Healthy Volunteers","status":"COMPLETED","sponsor":"Purdue Pharma LP","startDate":"2012-03","conditions":"ECG Effects","enrollment":328},{"nctId":"NCT02174718","phase":"NA","title":"Evaluation of a Transdermal Vitamin D3 Delivery System, D3forME","status":"WITHDRAWN","sponsor":"University of Wisconsin, Madison","startDate":"2015-11","conditions":"Vitamin D Deficiency","enrollment":""},{"nctId":"NCT03438604","phase":"PHASE1","title":"A Study to Evaluate the Effect of Heat Application on the Delivery Profile of Corplex™ Donepezil Transdermal Delivery System (TDS)","status":"COMPLETED","sponsor":"Corium, Inc.","startDate":"2018-02-13","conditions":"Alzheimer's Disease","enrollment":24},{"nctId":"NCT03397862","phase":"PHASE1","title":"A Skin Irritation Assessment of Once-Weekly Corplex™ Donepezil Transdermal Delivery System","status":"COMPLETED","sponsor":"Corium, Inc.","startDate":"2017-11-14","conditions":"Skin Irritation, Sensitization","enrollment":256},{"nctId":"NCT03432195","phase":"PHASE1","title":"A Clinical Study to Evaluate the Pharmacokinetics (PK) of Corplex™ Donepezil Transdermal Delivery System (TDS) Applied to Different Body Locations","status":"COMPLETED","sponsor":"Corium, Inc.","startDate":"2018-01-31","conditions":"Alzheimer's Disease","enrollment":66},{"nctId":"NCT03259958","phase":"PHASE1","title":"A Bioequivalence Study of Corplex™ Donepezil Transdermal Delivery System Compared to Aricept®","status":"COMPLETED","sponsor":"Corium, Inc.","startDate":"2017-10-30","conditions":"Alzheimer's Disease","enrollment":86},{"nctId":"NCT02968719","phase":"PHASE1","title":"A Phase 1, Corplex™ Donepezil Transdermal System Compared to Oral Aricept®","status":"COMPLETED","sponsor":"Corium, Inc.","startDate":"2016-11","conditions":"Alzheimer Disease","enrollment":107},{"nctId":"NCT01375946","phase":"PHASE1","title":"Pharmacokinetic Study Of AGILE AG200-15 After Weekly Application Under Various Conditions in Healthy Female Volunteers","status":"COMPLETED","sponsor":"Agile Therapeutics","startDate":"2011-05","conditions":"Healthy","enrollment":24},{"nctId":"NCT01181479","phase":"PHASE3","title":"Study to Evaluate the Contraceptive Efficacy/Safety of a Low Dose EE/LNG Transdermal Contraceptive Delivery System","status":"COMPLETED","sponsor":"Agile Therapeutics","startDate":"2010-08","conditions":"Contraception","enrollment":1504},{"nctId":"NCT02839135","phase":"PHASE1","title":"A Comparative Bioavailability and Adhesion Performance Study, Comparing a New Scopolamine Transdermal Delivery System Formulation to the Currently Established Reference Transdermal Delivery System in Healthy Adult Participants.","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2016-05-13","conditions":"Motion Sickness","enrollment":128},{"nctId":"NCT02132247","phase":"PHASE4","title":"Safety Study of Flector Patch in Children With Minor Soft Tissue Injuries","status":"COMPLETED","sponsor":"IBSA Institut Biochimique SA","startDate":"2014-05","conditions":"Athletic Injuries","enrollment":104},{"nctId":"NCT01623466","phase":"PHASE1, PHASE2","title":"Study to Evaluate Pharmacokinetics Profile, Wearability, and Safety of 2 Progestin-Only Patches","status":"COMPLETED","sponsor":"Agile Therapeutics","startDate":"2012-07","conditions":"Healthy","enrollment":36},{"nctId":"NCT01243580","phase":"PHASE1","title":"AG200-15 Transdermal Contraceptive Delivery System (TCDS) of Levonorgestrel and Ethinyl Estradiol","status":"COMPLETED","sponsor":"Agile Therapeutics","startDate":"2009-08","conditions":"Healthy","enrollment":36},{"nctId":"NCT01236768","phase":"PHASE3","title":"Transdermal Contraceptive Delivery System (TCDS), Also Known as AG200-15 Patch Arm","status":"COMPLETED","sponsor":"Agile Therapeutics","startDate":"2010-10","conditions":"Contraception","enrollment":407},{"nctId":"NCT01989923","phase":"NA","title":"Smoking Cessation in Women With Gynecological Conditions","status":"COMPLETED","sponsor":"University of Oklahoma","startDate":"2013-06","conditions":"Cervical Dysplasia","enrollment":31},{"nctId":"NCT00857753","phase":"PHASE1","title":"Relative Bioavailability of a Fentanyl Patch","status":"COMPLETED","sponsor":"Sandoz","startDate":"2006-09","conditions":"Pain","enrollment":40},{"nctId":"NCT02459938","phase":"PHASE1","title":"Safety and Efficacy of ZP-Glucagon to Injectable Glucagon for Hypoglycemia","status":"COMPLETED","sponsor":"Zosano Pharma Corporation","startDate":"2015-01","conditions":"Hypoglycemia","enrollment":16},{"nctId":"NCT00377988","phase":"","title":"A Postmarketing Study of the Risk of Venous Thromboembolism (Blood Clots), Myocardial Infarction (Heart Attacks), and Stroke Among Women Using ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) Compared With Women Who Take Oral Contraceptives for Birth Control","status":"COMPLETED","sponsor":"Johnson & Johnson Pharmaceutical Research & Development, L.L.C.","startDate":"2002-04","conditions":"Contraception, Female Contraception","enrollment":423},{"nctId":"NCT01592344","phase":"NA","title":"Bioness® StimRouter™ Neuromodulation System for Chronic Pain Therapy","status":"COMPLETED","sponsor":"Bioness Inc","startDate":"2012-04","conditions":"Chronic Pain","enrollment":94},{"nctId":"NCT02431624","phase":"PHASE1","title":"An Assessment of Buprenorphine Transdermal Delivery System (BTDS) Patch Adhesion","status":"COMPLETED","sponsor":"Mundipharma Research Limited","startDate":"2015-03","conditions":"Pain","enrollment":40},{"nctId":"NCT00546650","phase":"PHASE1","title":"Phase I Study to Compare NP101(Sumatriptan Iontophoretic Transdermal Patch) With Three Formulations of Imitrex®","status":"COMPLETED","sponsor":"NuPathe Inc.","startDate":"2007-11","conditions":"Healthy","enrollment":25},{"nctId":"NCT01533428","phase":"PHASE3","title":"A Study to Evaluate Efficacy and Safety of a Single Application of Capsaicin 8%Transdermal Delivery System Compared to Placebo in Reducing Pain Intensity in Subjects With Painful Diabetic Peripheral Neuropathy (PDPN)","status":"COMPLETED","sponsor":"Astellas Pharma Inc","startDate":"2012-02","conditions":"Diabetic Peripheral Neuropathy, Pain","enrollment":369},{"nctId":"NCT00943566","phase":"PHASE2","title":"A Safety and Efficacy Study of Sufentanil Transdermal System in Patients With Chronic Pain Due to Cancer","status":"WITHDRAWN","sponsor":"Labtec GmbH","startDate":"2010-01","conditions":"Chronic Pain","enrollment":""},{"nctId":"NCT00310531","phase":"PHASE3","title":"3-year Study of Menostar Versus Evista to Prevent Osteoporosis in Post-menopausal Women","status":"COMPLETED","sponsor":"Bayer","startDate":"2004-02","conditions":"Osteopenia","enrollment":500},{"nctId":"NCT00185237","phase":"PHASE3","title":"Treatment of Hot Flushes in Asian Women With Ultra-low Dose Estradiol Patch","status":"COMPLETED","sponsor":"Bayer","startDate":"2005-07","conditions":"Hot Flashes","enrollment":165},{"nctId":"NCT01854216","phase":"PHASE1","title":"Study to Evaluate the Pharmacokinetics, Safety, Tolerability of Repeated Dose Transdermal Rotigotine in Japanese and Caucasian Subjects","status":"COMPLETED","sponsor":"UCB BIOSCIENCES GmbH","startDate":"2002-12","conditions":"Healthy","enrollment":26},{"nctId":"NCT01761526","phase":"PHASE1","title":"Study to Evaluate the Pharmacokinetics (PK), Safety, Tolerability of Single-Dose Transdermal Rotigotine in Japanese and Caucasian Healthy Male / Female Subjects","status":"COMPLETED","sponsor":"UCB BIOSCIENCES GmbH","startDate":"2002-10","conditions":"Healthy","enrollment":50},{"nctId":"NCT02160067","phase":"PHASE1","title":"A Dose Proportionality and Bioavailability Assessment of Buprenorphine Transdermal Delivery System Second Generation Patches","status":"COMPLETED","sponsor":"Mundipharma Research Limited","startDate":"2014-05","conditions":"Pain","enrollment":20},{"nctId":"NCT01952886","phase":"PHASE2","title":"Patient Satisfaction, Efficacy and Compliance of Antiemetic Patch vs Pill in Malignant Glioma Patients","status":"WITHDRAWN","sponsor":"Duke University","startDate":"","conditions":"Malignant Glioma","enrollment":""},{"nctId":"NCT02221726","phase":"EARLY_PHASE1","title":"Study to Assess Adhesion Quality and Wear of Placebo JNJ-35685-AAA-G-023 Transdermal System in Healthy Adults","status":"COMPLETED","sponsor":"Janssen Research & Development, LLC","startDate":"2014-08","conditions":"Healthy","enrollment":16},{"nctId":"NCT01140217","phase":"PHASE3","title":"Efficacy and Safety Study of Norethindrone Acetate Transdermal Delivery System in Contraception","status":"COMPLETED","sponsor":"Watson Pharmaceuticals","startDate":"2010-05","conditions":"Contraceptive Usage","enrollment":1659},{"nctId":"NCT00455260","phase":"PHASE1","title":"A Multi-Dose Study to Assess Tolerability, Safety and Pharmacology of hGH-ViaDerm™ System in Adults With GH-Deficiency","status":"COMPLETED","sponsor":"Teva Neuroscience, Inc.","startDate":"2007-04","conditions":"Growth Hormone Deficiency","enrollment":60},{"nctId":"NCT00315874","phase":"PHASE3","title":"The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Chronic Low Back Pain.","status":"COMPLETED","sponsor":"Purdue Pharma LP","startDate":"1997-04","conditions":"Back Pain","enrollment":225},{"nctId":"NCT01750060","phase":"PHASE1","title":"Pharmacokinetic Characterization of the Active, Separated System With PK Controller (Fentanyl Iontophoretic Transdermal System, 40 Mcg Fentanyl Per Activation).","status":"COMPLETED","sponsor":"Incline Therapeutics, Inc.","startDate":"2012-12","conditions":"Pain, Postoperative","enrollment":54},{"nctId":"NCT01535820","phase":"PHASE1","title":"The Effect of an Adhesive Overlay on the Delivery of Contraceptive Hormones From ORTHO EVRA® in Healthy Women","status":"COMPLETED","sponsor":"Johnson & Johnson Pharmaceutical Research & Development, L.L.C.","startDate":"2011-03","conditions":"Healthy Volunteers","enrollment":54},{"nctId":"NCT01151098","phase":"PHASE3","title":"Safety of Buprenorphine Transdermal Systems in Subjects With Chronic Nonmalignant Pain - a 28-week Extension Study","status":"COMPLETED","sponsor":"Purdue Pharma LP","startDate":"2001-04","conditions":"Chronic Nonmalignant Pain","enrollment":189},{"nctId":"NCT01148537","phase":"PHASE1","title":"The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) on QT Intervals in Healthy Volunteers","status":"COMPLETED","sponsor":"Purdue Pharma LP","startDate":"2004-07","conditions":"Healthy Volunteers","enrollment":132},{"nctId":"NCT00313846","phase":"PHASE3","title":"Safety and Efficacy of Buprenorphine Transdermal System in Subjects With Moderate to Severe Osteoarthritis of Hip or Knee","status":"COMPLETED","sponsor":"Purdue Pharma LP","startDate":"2003-04","conditions":"Osteoarthritis","enrollment":529},{"nctId":"NCT00278824","phase":"PHASE2","title":"Fentanyl Transdermal Patch With CHADD™ for Breakthrough Pain in Patients With Moderate to Severe Non-Malignant Pain","status":"TERMINATED","sponsor":"ZARS Pharma Inc.","startDate":"2006-01","conditions":"Pain","enrollment":109},{"nctId":"NCT00488267","phase":"PHASE3","title":"Efficacy of ThermoProfen in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee","status":"COMPLETED","sponsor":"ZARS Pharma Inc.","startDate":"2007-06","conditions":"Osteoarthritis","enrollment":679},{"nctId":"NCT00224146","phase":"PHASE4","title":"Transdermal (TDS) Oxybutynin (Oxytrol(r)) in Overactive Bladder","status":"COMPLETED","sponsor":"Watson Pharmaceuticals","startDate":"2004-05","conditions":"Overactive Bladder, Urinary Incontinence, Quality of Life","enrollment":2878},{"nctId":"NCT01234142","phase":"PHASE1","title":"A Study Evaluating the Absorption Of Varenicline Through The Skin Following Once Daily Application Of A Patch For 14 Days","status":"COMPLETED","sponsor":"Pfizer","startDate":"2010-11","conditions":"Smoking Cessation","enrollment":45},{"nctId":"NCT00324038","phase":"PHASE4","title":"Buprenorphine in the Treatment of Osteoarthritis (OA) in the Elderly","status":"COMPLETED","sponsor":"Napp Pharmaceuticals Limited","startDate":"2006-03","conditions":"Osteoarthritis","enrollment":219}],"_emaApprovals":[],"_faersSignals":[{"count":41,"reaction":"APPLICATION SITE ERYTHEMA"},{"count":35,"reaction":"APPLICATION SITE PRURITUS"},{"count":26,"reaction":"OFF LABEL USE"},{"count":21,"reaction":"HEADACHE"},{"count":19,"reaction":"APPLICATION SITE PAIN"},{"count":18,"reaction":"PRODUCT ADHESION ISSUE"},{"count":17,"reaction":"APPLICATION SITE RASH"},{"count":16,"reaction":"WRONG TECHNIQUE IN PRODUCT USAGE PROCESS"},{"count":12,"reaction":"DRUG INEFFECTIVE"},{"count":12,"reaction":"PRODUCT QUALITY ISSUE"}],"crossReferences":{"chemblId":"CHEMBL2108729"},"_approvalHistory":[],"publicationCount":577,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Transdermal delivery system","genericName":"Transdermal delivery system","companyName":"Mundipharma AB","companyId":"mundipharma-ab","modality":"Small molecule","firstApprovalDate":"","enrichmentLevel":3,"visitCount":2,"regulatoryByCountry":[{"country_code":"CA","regulator":"Health Canada","status":"approved","approval_date":null,"mah":"","brand_name_local":"","application_number":""},{"country_code":"US","regulator":"FDA","status":"approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null}],"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":1,"lastValidatedAt":"2026-04-20T06:50:13.127573+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"enriching","dataCompleteness":{"mechanism":false,"indications":false,"safety":false,"trials":true,"score":1}}