{"id":"tranexamic-acid-injectable-product","safety":{"commonSideEffects":[{"rate":null,"effect":"Thromboembolic events (deep vein thrombosis, pulmonary embolism)"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Vomiting"},{"rate":null,"effect":"Diarrhea"},{"rate":null,"effect":"Hypotension"}]},"_chembl":{"chemblId":"CHEMBL877","moleculeType":"Small molecule","molecularWeight":"157.21"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Tranexamic acid is a competitive inhibitor of plasminogen and plasmin, which are key enzymes in the fibrinolytic cascade responsible for breaking down blood clots. By inhibiting these enzymes, the drug stabilizes fibrin clots and reduces fibrin degradation, leading to decreased bleeding. It is used to prevent or reduce blood loss in surgical and trauma settings.","oneSentence":"Tranexamic acid inhibits fibrinolysis by blocking plasminogen activation, thereby reducing excessive bleeding.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:38:56.727Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention and treatment of hemorrhage in surgical procedures"},{"name":"Trauma-related hemorrhage"},{"name":"Menorrhagia"}]},"trialDetails":[{"nctId":"NCT06337838","phase":"PHASE3","title":"Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial","status":"RECRUITING","sponsor":"Hamilton Health Sciences Corporation","startDate":"2025-06-09","conditions":"Chronic Kidney Diseases, Acute Kidney Injury, Bleeding","enrollment":100},{"nctId":"NCT06229483","phase":"PHASE3","title":"The Effects of Intraoperative Tranexamic Acid on Perioperative Bleeding In 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Used for Prevention and treatment of hemorrhage in surgical procedures, Trauma-related hemorrhage, Menorrhagia.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":2,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}