{"id":"topical-lidocaine","safety":{"commonSideEffects":[{"rate":null,"effect":"Local skin irritation or redness"},{"rate":null,"effect":"Allergic contact dermatitis"},{"rate":null,"effect":"Burning or stinging at application site"},{"rate":null,"effect":"Systemic toxicity (rare with topical use)"}]},"_chembl":{"chemblId":"CHEMBL79","moleculeType":"Small molecule","molecularWeight":"234.34"},"_dailymed":{"setId":"1baaa669-05af-4024-a0ba-ee3451756f6a","title":"LIDOCAINE 4% TOPICAL ANESTHETIC CREAM (LIDOCAINE 4%) CREAM [ONCOR PHARMACEUTICALS]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Lidocaine is a local anesthetic that works by inhibiting sodium influx through sodium-selective channels in the nerve cell membrane, thereby blocking the generation and propagation of action potentials. When applied topically, it anesthetizes the area of application by preventing sensory nerve signals from reaching the central nervous system. 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