{"id":"topical-intraoral-ketoprofen-gel","safety":{"commonSideEffects":[{"rate":"null","effect":"Gastrointestinal upset"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the production of prostaglandins, which are mediators of inflammation and pain. By reducing prostaglandin production, ketoprofen helps to alleviate pain and inflammation in the mouth.","oneSentence":"Topical intraoral ketoprofen gel works by reducing inflammation and pain in the mouth through the action of ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID).","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:39:28.215Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of oral mucositis"}]},"trialDetails":[{"nctId":"NCT01211795","phase":"PHASE3","title":"Topical Intra-Oral Ketoprofen for Migraine Prevention","status":"COMPLETED","sponsor":"Behar, Caren, M.D.","startDate":"2009-10","conditions":"Migraine","enrollment":67}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"topical intraoral ketoprofen gel","genericName":"topical intraoral ketoprofen gel","companyName":"Behar, Caren, M.D.","companyId":"behar-caren-m-d","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Topical intraoral ketoprofen gel works by reducing inflammation and pain in the mouth through the action of ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID). Used for Treatment of oral mucositis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}