{"id":"toothpaste-tablet","safety":{"commonSideEffects":[{"rate":null,"effect":"Mild gum irritation"},{"rate":null,"effect":"Tooth sensitivity"}]},"_chembl":null,"_dailymed":{"setId":"43d30abc-889a-5377-e063-6294a90ab804","title":"ME MOTHER EARTH (ZERO WASTE TOOTHPASTE TABLETS PEPPERMINT) TABLET, CHEWABLE [A PLUS MERCHANDISE LLC]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Toothpaste tablets are a solid, chewable form of oral hygiene product that contain similar active ingredients to conventional toothpaste, including fluoride for cavity prevention, abrasives for plaque removal, and surfactants for cleaning. When chewed and mixed with saliva, then brushed onto teeth, they deliver fluoride and mechanical cleaning action comparable to traditional paste formulations.","oneSentence":"Toothpaste tablets provide mechanical and chemical cleaning of teeth through abrasive and detergent ingredients when chewed and brushed.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:13:13.862Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dental caries prevention"},{"name":"Plaque removal and oral hygiene"}]},"trialDetails":[{"nctId":"NCT05401201","phase":"NA","title":"Dual-light Antibacterial Photodynamic Therapy as an Adjunctive Treatment to Corticosteroid Treatment in OLP","status":"ACTIVE_NOT_RECRUITING","sponsor":"Koite Health Oy","startDate":"2023-02-24","conditions":"Oral Lichen Planus, Dental Plaque, Oral Bacterial Infection","enrollment":60},{"nctId":"NCT07029360","phase":"NA","title":"Effectiveness of Coenzyme Q10 and Probiotics in Periodontal Therapy 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Invisalign Aligners: A Cross-Over Randomized Trial","status":"COMPLETED","sponsor":"Bezmialem Vakif University","startDate":"2021-10-18","conditions":"Aligner Staining","enrollment":20},{"nctId":"NCT05707221","phase":"NA","title":"Effect of Different Cleaning Regimes on Biofilm Formation of Acrylic Based Removable Orthodontic Appliance","status":"UNKNOWN","sponsor":"University of Baghdad","startDate":"2022-04-17","conditions":"Oral Disease","enrollment":39},{"nctId":"NCT04865796","phase":"NA","title":"Black Stains' Epidemiology, Clinical Evaluation and Dietary Habits: a Clinical Trial.","status":"COMPLETED","sponsor":"University of Pavia","startDate":"2021-05-15","conditions":"Black Stains","enrollment":45},{"nctId":"NCT05123651","phase":"NA","title":"Research on the Characteristics and Application of Lactobacillus Rhamnosus X253 as Oral Probiotics","status":"COMPLETED","sponsor":"Junlebao Dairy Group Co., Ltd.","startDate":"2020-11-01","conditions":"Dental 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Erosion","enrollment":75}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":32,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Denttabs Toothpaste Tablets","Sensodyne® Original","5% Potassium nitrate toothpaste","Sensodyne Original"],"phase":"marketed","status":"active","brandName":"Toothpaste Tablet","genericName":"Toothpaste Tablet","companyName":"Loma Linda University","companyId":"loma-linda-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Toothpaste tablets provide mechanical and chemical cleaning of teeth through abrasive and detergent ingredients when chewed and brushed. Used for Dental caries prevention, Plaque removal and oral hygiene.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}