{"id":"tocofersolan-and-tocopherol-alpha","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Tocofersolan is a form of vitamin E that helps protect cells from damage caused by free radicals. Tocopherol alpha is another form of vitamin E that has antioxidant properties, which helps to neutralize free radicals and protect cells from damage.","oneSentence":"Tocofersolan and tocopherol alpha work together to provide antioxidant properties.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:39:19.897Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of oxidative stress"}]},"trialDetails":[{"nctId":"NCT01457690","phase":"PHASE3","title":"Study of the Absorption of Vitamin E Water-soluble Form (Pegylated) in the Familial Hypocholesterolemia With Chylomicron Retention","status":"COMPLETED","sponsor":"Hospices Civils de Lyon","startDate":"2011-10","conditions":"Hypobetalipoproteinemias","enrollment":14},{"nctId":"NCT05429229","phase":"PHASE2","title":"Effect of Topical Antioxidants in Dry Eye Disease and Diabetic Retinopathy","status":"UNKNOWN","sponsor":"Adolfo Daniel Rodriguez-Carrizalez","startDate":"2021-11-01","conditions":"Dry Eye Syndromes, Diabetic Retinopathy, Oxidative Stress","enrollment":78},{"nctId":"NCT03582384","phase":"PHASE2","title":"Use of Tocofersolan (Vedrop®) to Prevent or Treat Refractive Vitamin E Deficiency in Infants and Children","status":"WITHDRAWN","sponsor":"Boston Children's Hospital","startDate":"2020-12","conditions":"Short Bowel Syndrome, Vitamin E Deficiency","enrollment":""}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":4,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Tocofersolan and tocopherol alpha","genericName":"Tocofersolan and tocopherol alpha","companyName":"Hospices Civils de Lyon","companyId":"hospices-civils-de-lyon","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Tocofersolan is a small molecule with the synonym E307, used in various interventions such as VisuXL and Lagricel PF. It has been studied in conditions including Short Bowel Syndrome, Vitamin E Deficiency, Dry Eye Syndromes, Diabetic Retinopathy, and Oxidative Stress, with one study specifically examining its use in preventing or treating refractive Vitamin E Deficiency in infants and children.","enrichmentLevel":3,"visitCount":5,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}