{"id":"tirofiban-intracoronary-bolus-only","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Bleeding"},{"rate":"5-10%","effect":"Thrombocytopenia"},{"rate":"5-10%","effect":"Anemia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By binding to the glycoprotein IIb/IIIa receptor, tirofiban prevents the final common pathway of platelet aggregation, thereby reducing the risk of thrombotic complications in patients undergoing coronary interventions.","oneSentence":"Tirofiban is a non-peptide antagonist of the glycoprotein IIb/IIIa receptor, inhibiting platelet aggregation.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:54:14.032Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute coronary syndrome"},{"name":"Unstable angina"}]},"trialDetails":[{"nctId":"NCT01109134","phase":"PHASE3","title":"Tirofiban Intracoronary Bolus-only Versus Intravenous Bolus Plus Infusion in STEMI Patients","status":"COMPLETED","sponsor":"Kosuyolu Heart Hospital","startDate":"2008-09","conditions":"Acute Myocardial Infarction","enrollment":49}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Aggrastat"],"phase":"phase_3","status":"active","brandName":"tirofiban intracoronary bolus-only","genericName":"tirofiban intracoronary bolus-only","companyName":"Kosuyolu Heart Hospital","companyId":"kosuyolu-heart-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Tirofiban is a non-peptide antagonist of the glycoprotein IIb/IIIa receptor, inhibiting platelet aggregation. Used for Acute coronary syndrome, Unstable angina.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}