{"id":"timonacic","rwe":[{"pmid":"40807327","year":"2025","title":"Versatile High-Performance Liquid Chromatography and Ultraviolet Detection-Based Method for the Determination of Thioproline in Pharmaceutical and Cosmetic Products.","finding":"","journal":"Molecules (Basel, Switzerland)","studyType":"Clinical Study"},{"pmid":"40609364","year":"2025","title":"Rapid and non-destructive detection of formaldehyde adulteration in shrimp based on deep learning-assisted portable Raman spectroscopy.","finding":"","journal":"Food chemistry","studyType":"Clinical Study"},{"pmid":"34560694","year":"2022","title":"Healthcare practitioners' diagnostic and treatment practice patterns of nonalcoholic fatty liver disease in Poland: a cross-sectional survey.","finding":"","journal":"European journal of gastroenterology & hepatology","studyType":"Clinical Study"},{"pmid":"36703413","year":"2020","title":"Amino acid dependent formaldehyde metabolism in mammals.","finding":"","journal":"Communications chemistry","studyType":"Clinical Study"},{"pmid":"9608431","year":"1998","title":"Spectrophotometric investigation of the formed chelate between timonacic and palladium(II) and its analytical applications.","finding":"","journal":"Journal of pharmaceutical and biomedical analysis","studyType":"Clinical Study"}],"tags":[{"label":"timonacic","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"tiazolidin","offLabel":[],"synonyms":["timonacic","4-Thiazolidinecarboxylic acid","thiaproline","tiazolidin"],"timeline":[],"approvals":[],"brandName":"Tiazolidin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"timonacic","explanation":"Imagine your body's cells have locks on them, and each lock has a unique key. Timonacic is like a key that fits into one of these locks, but we don't yet know which lock it is or what it does when it's inside. This binding process is thought to affect the way cells work, but the details are still being studied.","oneSentence":"Timonacic is thought to work by binding to a specific target, although the exact target and mechanism are not yet fully understood.","technicalDetail":"Timonacic is a small molecule that modulates the activity of a specific protein or protein complex, although the precise molecular details of this interaction are currently unknown."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2670","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=TIMONACIC","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:57:02.781257","biosimilars":[],"competitors":[],"genericName":"timonacic","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"E5913T3IBL","CHEBI":"CHEBI:64564","INN_ID":"3782","UMLSCUI":"C0076425","ChEMBL_ID":"CHEMBL358722","KEGG_DRUG":"D08601","DRUGBANK_ID":"DB12856","PUBCHEM_CID":"9934"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":5,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2025 Jul 28","pmid":"40807327","title":"Versatile High-Performance Liquid Chromatography and Ultraviolet Detection-Based Method for the Determination of Thioproline in Pharmaceutical and Cosmetic Products.","journal":"Molecules (Basel, Switzerland)"},{"date":"2025 Nov 15","pmid":"40609364","title":"Rapid and non-destructive detection of formaldehyde adulteration in shrimp based on deep learning-assisted portable Raman spectroscopy.","journal":"Food chemistry"},{"date":"2022 Apr 1","pmid":"34560694","title":"Healthcare practitioners' diagnostic and treatment practice patterns of nonalcoholic fatty liver disease in Poland: a cross-sectional survey.","journal":"European journal of gastroenterology & hepatology"},{"date":"2020 Jun 16","pmid":"36703413","title":"Amino acid dependent formaldehyde metabolism in mammals.","journal":"Communications chemistry"},{"date":"1998 May","pmid":"9608431","title":"Spectrophotometric investigation of the formed chelate between timonacic and palladium(II) and its analytical applications.","journal":"Journal of pharmaceutical and biomedical analysis"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Tiazolidin is a small molecule with the synonyms HEPACOM, NORGAMEN, NSC-25855, TIMONACIC, and TIMONACICO.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}