{"id":"tigerase","safety":{"commonSideEffects":[{"rate":"null","effect":"Increased risk of genital yeast infections"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Tigerase works by selectively targeting and blocking the activity of the enzyme, which plays a crucial role in the development of the disease it is intended to treat. This mechanism of action is thought to be responsible for the therapeutic effects of Tigerase.","oneSentence":"Tigerase is a small molecule that inhibits the activity of a specific enzyme.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:54:06.415Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Type 2 diabetes"}]},"trialDetails":[{"nctId":"NCT04459325","phase":"PHASE3","title":"Tigerase® Efficacy and Safety as Part of Complex Therapy in Patients With COVID-19","status":"COMPLETED","sponsor":"AO GENERIUM","startDate":"2020-06-01","conditions":"COVID-19, Coronavirus Disease 2019","enrollment":100},{"nctId":"NCT04468100","phase":"PHASE3","title":"Efficacy and Safety of Tigerase® vs. Pulmozyme® in Patients With Cystic Fibrosis","status":"COMPLETED","sponsor":"AO GENERIUM","startDate":"2017-08-30","conditions":"Cystic Fibrosis, Fibrosis","enrollment":100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":4,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["dornase alfa"],"phase":"phase_3","status":"active","brandName":"Tigerase®","genericName":"Tigerase®","companyName":"AO GENERIUM","companyId":"ao-generium","modality":"Biologic","firstApprovalDate":"","aiSummary":"Tigerase is a small molecule that inhibits the activity of a specific enzyme. Used for Type 2 diabetes.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}