{"id":"ticlopidine-ginko-biloba","safety":{"commonSideEffects":[{"rate":"null","effect":"Thrombocytopenia"},{"rate":"null","effect":"Neutropenia"},{"rate":"null","effect":"Diarrhea"},{"rate":"null","effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Ticlopidine works by binding to the P2Y12 receptor on platelets, preventing ADP from binding and activating the receptor. This leads to a decrease in platelet aggregation and a subsequent reduction in the risk of thrombotic events. Ginkgo biloba, on the other hand, has been shown to have antioxidant and anti-inflammatory properties, which may contribute to its potential therapeutic effects.","oneSentence":"Ticlopidine inhibits platelet aggregation by irreversibly blocking ADP receptors on platelets, while Ginkgo biloba has antioxidant and anti-inflammatory properties.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:38:43.011Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of stroke in patients with atherosclerotic disease"}]},"trialDetails":[{"nctId":"NCT02133989","phase":"PHASE3","title":"Clopidogrel Resistance and Embolism in Carotid Artery Stenting","status":"UNKNOWN","sponsor":"Samsung Medical Center","startDate":"2014-06","conditions":"Carotid Stenosis","enrollment":86}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Yuclid"],"phase":"phase_3","status":"active","brandName":"Ticlopidine + Ginko biloba","genericName":"Ticlopidine + Ginko biloba","companyName":"Samsung Medical Center","companyId":"samsung-medical-center","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ticlopidine inhibits platelet aggregation by irreversibly blocking ADP receptors on platelets, while Ginkgo biloba has antioxidant and anti-inflammatory properties. Used for Prevention of stroke in patients with atherosclerotic disease.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}