{"id":"tiaramide","rwe":[{"pmid":"26874639","year":"2016","title":"Nonsteroidal Anti-Inflammatory Drugs Quickly Resolve Symptoms Associated with EBV-Induced Infectious Mononucleosis in Patients with Atopic Predispositions.","finding":"","journal":"The American journal of case reports","studyType":"Clinical Study"},{"pmid":"18789319","year":"2008","title":"Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells.","finding":"","journal":"European journal of pharmacology","studyType":"Clinical Study"},{"pmid":"17291297","year":"2007","title":"Safety of selective cyclooxygenase-2 inhibitors and a basic non-steroidal anti-inflammatory drug (NSAID) in Japanese patients with NSAID-induced urticaria and/or angioedema: Comparison of meloxicam, etodolac and tiaramide.","finding":"","journal":"The Journal of dermatology","studyType":"Clinical Study"},{"pmid":"15618683","year":"2002","title":"Strategy for structure elucidation of drug metabolites derived from protonated molecules and (MS)n fragmentation of zotepine, tiaramide and their metabolites.","finding":"","journal":"Drug metabolism and pharmacokinetics","studyType":"Clinical Study"},{"pmid":"9742556","year":"1998","title":"Preparation and evaluation of beads made of different calcium alginate compositions for oral sustained release of tiaramide.","finding":"","journal":"Pharmaceutical development and technology","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Analgesics","category":"pharmacology"},{"label":"Analgesics, Non-Narcotic","category":"pharmacology"},{"label":"Anti-Asthmatic Agents","category":"pharmacology"},{"label":"Anti-Inflammatory Agents","category":"pharmacology"},{"label":"Anti-Inflammatory Agents, Non-Steroidal","category":"pharmacology"},{"label":"Antirheumatic Agents","category":"pharmacology"},{"label":"Bronchodilator Agents","category":"pharmacology"},{"label":"Peripheral Nervous System Agents","category":"pharmacology"},{"label":"Respiratory System Agents","category":"pharmacology"},{"label":"Sensory System Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"tialamide","offLabel":[],"synonyms":["tiaramide hydrochloride","tiaramide","tialamide","tiaramide HCl"],"timeline":[],"approvals":[],"brandName":"Tialamide","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells have locks on them, and Tialamide is a key that fits into one of those locks. When it binds, it helps to unlock a specific process in the cell, which can help to treat a particular disease or condition. This is a simplified explanation of how Tialamide works at a molecular level.","oneSentence":"Tialamide is a small molecule that works by binding to a specific target to produce its therapeutic effect.","technicalDetail":"Tialamide's exact mechanism of action is not specified, but it is believed to work through a specific interaction with a target protein, potentially modulating a signaling pathway or enzyme activity."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2653","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=TIARAMIDE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:54:29.537536","biosimilars":[],"competitors":[],"genericName":"tiaramide","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"010986","UNII":"BB17WGM686","CHEBI":"CHEBI:32222","INN_ID":"3070","UMLSCUI":"C0076655","ChEMBL_ID":"CHEMBL274239","KEGG_DRUG":"D01341","PUBCHEM_CID":"5469","SECONDARY_CAS_RN":"35941-71-0","MESH_SUPPLEMENTAL_RECORD_UI":"C003468"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2016 Feb 14","pmid":"26874639","title":"Nonsteroidal Anti-Inflammatory Drugs Quickly Resolve Symptoms Associated with EBV-Induced Infectious Mononucleosis in Patients with Atopic Predispositions.","journal":"The American journal of case reports"},{"date":"2008 Oct 31","pmid":"18789319","title":"Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells.","journal":"European journal of pharmacology"},{"date":"2007 Mar","pmid":"17291297","title":"Safety of selective cyclooxygenase-2 inhibitors and a basic non-steroidal anti-inflammatory drug (NSAID) in Japanese patients with NSAID-induced urticaria and/or angioedema: Comparison of meloxicam, etodolac and tiaramide.","journal":"The Journal of dermatology"},{"date":"2002","pmid":"15618683","title":"Strategy for structure elucidation of drug metabolites derived from protonated molecules and (MS)n fragmentation of zotepine, tiaramide and their metabolites.","journal":"Drug metabolism and pharmacokinetics"},{"date":"1998 Aug","pmid":"9742556","title":"Preparation and evaluation of beads made of different calcium alginate compositions for oral sustained release of tiaramide.","journal":"Pharmaceutical development and technology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Tialamide is a small molecule with the synonyms RHC 2592A, RHC-2592A, TIALAMIDE, TIARAMIDA, TIARAMIDE, and TIARAMIDE.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}