{"id":"thyme-honey-mouth-rinse","safety":{"commonSideEffects":[{"rate":null,"effect":"Allergic reaction to thyme or honey"},{"rate":null,"effect":"Oral irritation or burning sensation"}]},"_chembl":{"chemblId":"CHEMBL2108391","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Thyme contains thymol and carvacrol, which have documented antimicrobial properties against oral bacteria and fungi. Honey provides additional antimicrobial activity via hydrogen peroxide production and polyphenol content, while both ingredients possess anti-inflammatory properties that may reduce gum inflammation and support oral wound healing.","oneSentence":"Thyme honey mouth rinse exerts antimicrobial and anti-inflammatory effects in the oral cavity through the bioactive compounds in thyme and honey.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:12:32.251Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Oral hygiene and antimicrobial mouth rinse"},{"name":"Gingivitis and gum inflammation management"}]},"trialDetails":[{"nctId":"NCT07358494","phase":"NA","title":"Effect of Diluted Thyme Honey On Dry Mouth In Intensive Care Unit Patients Exposed to Oxygen Flow Therapy","status":"COMPLETED","sponsor":"Esra Yaprak Gokturk","startDate":"2022-10-01","conditions":"Nursing Care","enrollment":64},{"nctId":"NCT06726876","phase":"PHASE3","title":"Therapeutic Effect of Manuka Honey Oral Rinse in Periodontitis Patients Undergoing Hemodialysis","status":"RECRUITING","sponsor":"Ain Shams University","startDate":"2024-10-01","conditions":"Periodontitis, Hemodialysis","enrollment":150},{"nctId":"NCT05859711","phase":"PHASE4","title":"Effectiveness of Thyme Honey in Management of Xerostomia in Post Radiation Cancer Patients","status":"COMPLETED","sponsor":"Ain Shams University","startDate":"2021-02-20","conditions":"Head and Neck Cancer Patients","enrollment":90},{"nctId":"NCT06201923","phase":"PHASE4","title":"The Efficacy of Thyme Honey Mouth Rinse on Polypharmacy-induced Xerostomia","status":"COMPLETED","sponsor":"Ain Shams University","startDate":"2024-01-15","conditions":"Xerostomia","enrollment":32},{"nctId":"NCT06129097","phase":"NA","title":"Thyme Honey Mouthwash in Management of Periodontitis in Renal Patients","status":"COMPLETED","sponsor":"British University In Egypt","startDate":"2024-01-01","conditions":"Periodontal Diseases, Periodontal Pocket, Periodontal Attachment Loss","enrollment":20},{"nctId":"NCT05885906","phase":"PHASE3","title":"Aloe Vera Versus Thyme Honey Mouthwash in Management of Xerostomia in Type 2 Diabetics","status":"UNKNOWN","sponsor":"Ain Shams University","startDate":"2023-07-24","conditions":"Xerostomia","enrollment":45},{"nctId":"NCT05648682","phase":"NA","title":"Comparison of the Effectiveness of Three Different Gargates in Radiotherapy-Associated Oral Mucositis","status":"COMPLETED","sponsor":"Saglik Bilimleri Universitesi Gulhane Tip Fakultesi","startDate":"2020-01-01","conditions":"Head and Neck Cancers, Oral Mucositis","enrollment":48},{"nctId":"NCT05247008","phase":"NA","title":"Effectiveness of Thyme Honey in Management of Xerostomia in ESRD","status":"COMPLETED","sponsor":"Ain Shams University","startDate":"2021-09-10","conditions":"Xerostomia","enrollment":40}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"thyme honey mouth rinse","genericName":"thyme honey mouth rinse","companyName":"Ain Shams University","companyId":"ain-shams-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Thyme honey mouth rinse exerts antimicrobial and anti-inflammatory effects in the oral cavity through the bioactive compounds in thyme and honey. Used for Oral hygiene and antimicrobial mouth rinse, Gingivitis and gum inflammation management.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}