{"id":"three-consecutive-lots-of-ev71-vaccine","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain, erythema, or swelling"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Irritability or fussiness"},{"rate":null,"effect":"Myalgia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"The vaccine contains inactivated EV71 virus particles that trigger both humoral (antibody) and cellular immune responses. This immunization protects against hand, foot, and mouth disease (HFMD) and other EV71-associated complications by enabling the body to recognize and neutralize the virus upon exposure.","oneSentence":"An inactivated enterovirus 71 (EV71) vaccine that stimulates the immune system to produce antibodies against EV71, preventing infection and disease.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:38:31.277Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of hand, foot, and mouth disease (HFMD) caused by enterovirus 71"},{"name":"Prevention of EV71-associated neurological complications in pediatric populations"}]},"trialDetails":[{"nctId":"NCT01636245","phase":"PHASE3","title":"Immunogenicity and Safety of Three Consecutive Lots of a New Inactivated Enterovirus Type 71 (EV71) Vaccine","status":"COMPLETED","sponsor":"Sinovac Biotech Co., Ltd","startDate":"2012-07","conditions":"Hand, Foot and Mouth Disease","enrollment":1400}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Vaccine groups"],"phase":"phase_3","status":"active","brandName":"three consecutive lots of EV71 vaccine","genericName":"three consecutive lots of EV71 vaccine","companyName":"Sinovac Biotech Co., Ltd","companyId":"sinovac-biotech-co-ltd","modality":"Biologic","firstApprovalDate":"","aiSummary":"An inactivated enterovirus 71 (EV71) vaccine that stimulates the immune system to produce antibodies against EV71, preventing infection and disease. Used for Prevention of hand, foot, and mouth disease (HFMD) caused by enterovirus 71, Prevention of EV71-associated neurological complications in pediatric populations.","enrichmentLevel":3,"visitCount":2,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}