{"id":"thiamphenicol-glycinate","rwe":[],"tags":[{"label":"thiamphenicol glycinate","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Anti-Bacterial Agents","category":"pharmacology"},{"label":"Anti-Infective Agents","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"urfamicin","offLabel":[],"synonyms":["thiamphenicol glycinate","thiamphenicol glycine ester","thiophenicol glycinate","urfamicin","thiamphenicol aminoacetate hydrochloride","thiamphenicol aminoacetate HCl"],"timeline":[],"approvals":[],"brandName":"Urfamicin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"thiamphenicol glycinate","explanation":"Imagine your body's cells are like factories that make proteins to keep you healthy. Bacteria are like tiny invaders that try to take over these factories. Urfamicin is a special tool that blocks the bacteria's ability to make proteins, helping to stop the infection.","oneSentence":"Urfamicin works by inhibiting protein synthesis in bacteria.","technicalDetail":"Urfamicin exerts its antibacterial effects by binding to the 50S subunit of the bacterial ribosome, thereby inhibiting peptide bond formation and protein synthesis."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2625","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=thiamphenicol glycinate","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:52:33.174528","biosimilars":[],"competitors":[],"genericName":"thiamphenicol glycinate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"005347","UNII":"88VGC22BWE","CHEBI":"CHEBI:135669","INN_ID":"935","RXNORM":"10463","UMLSCUI":"C0612489","ChEMBL_ID":"CHEMBL1697822","KEGG_DRUG":"D08583","DRUGBANK_ID":"DB08621","PDB_CHEM_ID":" TH8","PUBCHEM_CID":"115817","SNOMEDCT_US":"363552000","SECONDARY_CAS_RN":"2611-61-2","MESH_DESCRIPTOR_UI":"D013839","MESH_SUPPLEMENTAL_RECORD_UI":"C028813"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"pharmacokinetics":{"source":"DrugCentral","halfLife":"0.28 hours","clearance":"9.6 mL/min/kg","fractionUnbound":"0.27%","volumeOfDistribution":"0.13 L/kg"},"publicationCount":39,"therapeuticAreas":["Infectious Disease"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Urfamicin is a small molecule. Its mechanism of action is not specified in the provided information.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}