{"id":"theratope-stn-klh-vaccine","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Fatigue"},{"rate":"10-20%","effect":"Pain"},{"rate":"5-10%","effect":"Nausea"},{"rate":"5-10%","effect":"Vomiting"},{"rate":"5-10%","effect":"Diarrhea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This vaccine is designed to induce the production of antibodies that can recognize and bind to the STn antigen, marking cancer cells for destruction by the immune system. The STn antigen is a tumor-associated antigen that is overexpressed on the surface of many types of cancer cells, making it a promising target for immunotherapy.","oneSentence":"The THERATOPE STn-KLH vaccine works by stimulating an immune response against the STn antigen, which is expressed on the surface of cancer cells.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:38:24.235Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Non-small cell lung cancer"}]},"trialDetails":[{"nctId":"NCT00003638","phase":"PHASE3","title":"Vaccine Therapy in Treating Women With Metastatic Breast Cancer","status":"COMPLETED","sponsor":"Oncothyreon Canada Inc.","startDate":"1999-01","conditions":"Breast Cancer","enrollment":950},{"nctId":"NCT00046371","phase":"PHASE2","title":"Safety and Immunological Response Rate Study of THERATOPE® Vaccine in Metastatic Breast Cancer Patients","status":"COMPLETED","sponsor":"Oncothyreon Canada Inc.","startDate":"2002-08","conditions":"Breast Neoplasms","enrollment":""}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":4,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"THERATOPE STn-KLH vaccine","genericName":"THERATOPE STn-KLH vaccine","companyName":"Oncothyreon Canada Inc.","companyId":"oncothyreon-canada-inc","modality":"Biologic","firstApprovalDate":"","aiSummary":"The THERATOPE STn-KLH vaccine works by stimulating an immune response against the STn antigen, which is expressed on the surface of cancer cells. Used for Non-small cell lung cancer.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}