{"id":"theratears-lubricant-eye-drop","safety":{"commonSideEffects":[{"rate":null,"effect":"Transient eye irritation"},{"rate":null,"effect":"Blurred vision"},{"rate":null,"effect":"Eye discomfort"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"TheraTears is a preservative-free lubricating eye drop formulated to mimic the composition of natural tears. It contains a balanced mixture of electrolytes and demulcents designed to stabilize the tear film and provide sustained lubrication to the cornea and conjunctiva. The formulation helps restore the protective barrier function of tears in patients with dry eye disease.","oneSentence":"TheraTears lubricates and protects the ocular surface by supplementing natural tear film components, particularly lipids and aqueous components, to relieve dry eye symptoms.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:38:42.696Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye disease / Keratoconjunctivitis sicca"},{"name":"Ocular surface irritation and discomfort"}]},"trialDetails":[{"nctId":"NCT06221345","phase":"PHASE4","title":"Hyaluronic Acid-containing Artificial Tears in Post-cataract Surgery Dry Eye Disease","status":"COMPLETED","sponsor":"Chang Gung Memorial Hospital","startDate":"2021-12-07","conditions":"Dry Eye Disease, Cataract","enrollment":70},{"nctId":"NCT02121847","phase":"PHASE4","title":"Investigation of Maintaining Visual Performance Achieved With Cyclosporine Therapy","status":"COMPLETED","sponsor":"Allergan","startDate":"2014-04-03","conditions":"Dry Eye Syndromes","enrollment":40},{"nctId":"NCT01459588","phase":"PHASE3","title":"Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease","status":"COMPLETED","sponsor":"Allergan","startDate":"2011-10-01","conditions":"Dry Eye Syndromes","enrollment":315},{"nctId":"NCT02455050","phase":"PHASE3","title":"A Study to Compare a New Eye Drop Formulation With Systane® Gel Drops and Genteal® Lubricant Gel Drops for Moderate to Severe Dry Eye Relief","status":"COMPLETED","sponsor":"Allergan","startDate":"2014-12","conditions":"Dry Eye Syndromes","enrollment":79},{"nctId":"NCT00932477","phase":"NA","title":"Safety and Tolerability of Artificial Tears in Dry Eye Subjects","status":"COMPLETED","sponsor":"Allergan","startDate":"2009-08","conditions":"Dry Eye Syndrome","enrollment":47},{"nctId":"NCT01010282","phase":"NA","title":"Safety and Efficacy of Two Artificial Tears in Dry Eye Subjects","status":"COMPLETED","sponsor":"Allergan","startDate":"2009-11","conditions":"Dry Eye Syndrome","enrollment":288},{"nctId":"NCT01799863","phase":"PHASE2, PHASE3","title":"Artificial Tears Versus Preservative Free Ketorolac Trometamol 0.45% for Acute Viral Conjunctivitis","status":"COMPLETED","sponsor":"Fundação Altino Ventura","startDate":"2012-06","conditions":"Conjunctivitis, Viral","enrollment":50},{"nctId":"NCT02014922","phase":"PHASE4","title":"A Study to Determine the Relief of Dry Eye Symptoms With the Use of TheraTears® Products (DUNLIN)","status":"COMPLETED","sponsor":"University of Waterloo","startDate":"2013-12","conditions":"Dry Eye Syndromes","enrollment":33},{"nctId":"NCT00544713","phase":"NA","title":"Evaluate the Safety and Efficacy of a New Artificial Tear for Use After LASIK Surgery","status":"COMPLETED","sponsor":"Allergan","startDate":"2007-09","conditions":"Dry Eye Syndrome","enrollment":228},{"nctId":"NCT00756678","phase":"PHASE4","title":"Efficacy and Acceptability of Two Lubricant Eye Drops","status":"COMPLETED","sponsor":"Allergan","startDate":"2008-09","conditions":"Dry Eye Syndromes","enrollment":51},{"nctId":"NCT00938704","phase":"PHASE4","title":"Study to Compare the Efficacy and Safety of Two Non-Preserved Artificial Tears for the Treatment of Dry Eye Signs and Symptoms","status":"COMPLETED","sponsor":"Allergan","startDate":"2009-06","conditions":"Dry Eye Syndromes","enrollment":71},{"nctId":"NCT01384851","phase":"NA","title":"Efficacy of the Chronic Application of Tear Formulations","status":"UNKNOWN","sponsor":"Glasgow Caledonian University","startDate":"2011-07","conditions":"Dry Eye","enrollment":38}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"TheraTears® Lubricant Eye Drop","genericName":"TheraTears® Lubricant Eye Drop","companyName":"University of Waterloo","companyId":"university-of-waterloo","modality":"Small molecule","firstApprovalDate":"","aiSummary":"TheraTears lubricates and protects the ocular surface by supplementing natural tear film components, particularly lipids and aqueous components, to relieve dry eye symptoms. Used for Dry eye disease / Keratoconjunctivitis sicca, Ocular surface irritation and discomfort.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}