{"id":"tetracyclin-ointment","safety":{"commonSideEffects":[{"rate":null,"effect":"Local skin irritation"},{"rate":null,"effect":"Contact dermatitis"},{"rate":null,"effect":"Photosensitivity (systemic form)"}]},"_chembl":{"chemblId":"CHEMBL5093910","moleculeType":"Unknown","molecularWeight":"444.44"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Tetracyclines are broad-spectrum antibiotics that work by reversibly binding to the bacterial 30S ribosomal subunit, blocking the attachment of aminoacyl-tRNA to the ribosome. This inhibits protein synthesis and leads to bacteriostatic effects against a wide range of gram-positive and gram-negative bacteria. When formulated as an ointment, tetracycline is applied topically to treat localized bacterial skin infections and prevent infection in wounds.","oneSentence":"Tetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing peptide bond formation and bacterial growth.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:11:54.361Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Topical treatment of bacterial skin infections"},{"name":"Wound infection prevention"},{"name":"Superficial skin and soft tissue infections"}]},"trialDetails":[{"nctId":"NCT03494972","phase":"NA","title":"A Tetracycline Drain Reduces Alveolar Osteitis in Third Molar Surgery","status":"COMPLETED","sponsor":"University of Oslo","startDate":"2016-01-02","conditions":"Post-Operative Wound Infection","enrollment":200}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":291,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Amoxicillin","Esomeprazole","Bismuth","marsupialization procedure"],"phase":"marketed","status":"active","brandName":"Tetracyclin ointment","genericName":"Tetracyclin ointment","companyName":"University of Oslo","companyId":"university-of-oslo","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Tetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing peptide bond formation and bacterial growth. Used for Topical treatment of bacterial skin infections, Wound infection prevention, Superficial skin and soft tissue infections.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}