{"id":"test-naproxen-sodium-tablet","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Gastrointestinal upset"},{"rate":"10-20%","effect":"Headache"},{"rate":"5-10%","effect":"Dizziness"},{"rate":"5-10%","effect":"Nausea"},{"rate":"2-5%","effect":"Vomiting"},{"rate":"2-5%","effect":"Abdominal pain"},{"rate":"2-5%","effect":"Diarrhea"},{"rate":"2-5%","effect":"Constipation"},{"rate":"2-5%","effect":"Flatulence"},{"rate":"1-2%","effect":"Rash"}]},"_chembl":{"chemblId":"CHEMBL1200806","moleculeType":"Small molecule","molecularWeight":"252.25"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By inhibiting COX, naproxen sodium reduces the production of prostaglandins, leading to a decrease in pain and inflammation. 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LLC","startDate":"2008-06","conditions":"Osteoarthritis","enrollment":22},{"nctId":"NCT02351024","phase":"PHASE1","title":"Phase I Study PK Study With OXP005 and Naprosyn","status":"COMPLETED","sponsor":"Oxford Pharmascience Ltd","startDate":"2015-02","conditions":"Pharmacokinetics","enrollment":""},{"nctId":"NCT02355236","phase":"PHASE4","title":"Gastro-protective Effect and Pain Relief Effect of Naxozol Compared to Celecoxib in Patients With Osteoarthritis","status":"UNKNOWN","sponsor":"Severance Hospital","startDate":"2015-02","conditions":"Osteoarthritis","enrollment":106},{"nctId":"NCT00804401","phase":"PHASE1","title":"Bioequivalence Study Between Two Oral Formulations of Naproxen 500 mg Tablets Under Fasting Conditions","status":"COMPLETED","sponsor":"Perrigo Company","startDate":"2004-06","conditions":"Bioequivalency","enrollment":34},{"nctId":"NCT00803764","phase":"PHASE1","title":"Bioequivalence Study Between Two Oral Formulations of Naproxen 500 mg Tablets Under Fed 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tablets are used to treat conditions such as osteoarthritis and post-operative dental pain. They work by inhibiting the enzyme cyclooxygenase, which is involved in the production of prostaglandins that cause pain and inflammation.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}