{"id":"tenoten-for-children","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL521875","moleculeType":"Small molecule","molecularWeight":"460.53"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Tenoten is formulated as a homeopathic remedy containing antibodies to brain-derived neurotrophic factor (BDNF) and S-100 protein, which are believed to influence stress response and neuroplasticity. The mechanism is based on homeopathic principles rather than conventional pharmacology, with proposed effects on anxiety-related neural circuits. Clinical use in pediatrics focuses on behavioral and emotional symptoms associated with stress and anxiety.","oneSentence":"Tenoten for children is a homeopathic preparation that modulates stress-related neurobiological pathways to reduce anxiety and improve emotional regulation in pediatric patients.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:11:42.708Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Anxiety and emotional stress in children"},{"name":"Behavioral disorders associated with stress in pediatric patients"}]},"trialDetails":[{"nctId":"NCT03159104","phase":"PHASE3","title":"Efficacy and Safety of Tenoten for Children in the Treatment of Specific Developmental Disorders of Scholastic Skills in Children","status":"COMPLETED","sponsor":"Materia Medica Holding","startDate":"2015-08-25","conditions":"Specific Developmental Disorders of Scholastic Skills","enrollment":240},{"nctId":"NCT05605938","phase":"PHASE4","title":"Efficacy and Safety of Tenoten in the Treatment of Children With Anxiety Disorders","status":"COMPLETED","sponsor":"Materia Medica Holding","startDate":"2010-07-28","conditions":"Anxiety Disorder of Childhood","enrollment":98},{"nctId":"NCT03159611","phase":"PHASE3","title":"Efficacy and Safety Clinical Trial of Tenoten for Children Liquid Dosage Form Therapy in Infants With Sequelae of Perinatal Brain Injury","status":"COMPLETED","sponsor":"Materia Medica Holding","startDate":"2016-02-19","conditions":"Sequelae of Perinatal Brain Injury","enrollment":182}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":6,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Tenoten for children","genericName":"Tenoten for children","companyName":"Materia Medica Holding","companyId":"materia-medica-holding","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Tenoten for children is a homeopathic preparation that modulates stress-related neurobiological pathways to reduce anxiety and improve emotional regulation in pediatric patients. Used for Anxiety and emotional stress in children, Behavioral disorders associated with stress in pediatric patients.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":2},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}