{"id":"tenonitrozole","rwe":[],"tags":[{"label":"tenonitrozole","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"P01AX08","category":"atc"},{"label":"Active","category":"status"},{"label":"Infection by Trichomonas","category":"indication"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"atrican","offLabel":[],"synonyms":["tenonitrozole","thenitrazole","thenitrazolum","tenonitrozol","atrican"],"timeline":[],"approvals":[],"brandName":"Atrican","ecosystem":[{"indication":"Infection by Trichomonas","otherDrugs":[{"name":"metronidazole","slug":"metronidazole","company":"Gd Searle Llc"},{"name":"secnidazole","slug":"secnidazole","company":"Symbiomix Therapeutics Llc"},{"name":"tinidazole","slug":"tinidazole","company":"Mission Pharma"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","drugClass":"tenonitrozole","explanation":"Think of African like a key that fits into a lock on the parasite's cell. When it binds, it disrupts the parasite's ability to multiply and cause infection. This helps the body's immune system fight off the infection more effectively.","oneSentence":"African works by targeting the parasite that causes Trichomonas infections.","technicalDetail":"African is a small molecule that likely targets a specific protein or enzyme involved in the parasite's life cycle, disrupting its ability to replicate and cause infection."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2594","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=TENONITROZOLE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:50:08.235943","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T10:58:32.098792+00:00","fieldsConflicting":0,"overallConfidence":0.95},"biosimilars":[],"competitors":[{"drugName":"atovaquone","drugSlug":"atovaquone","fdaApproval":"1992-11-25","genericCount":9,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"trimetrexate","drugSlug":"trimetrexate","fdaApproval":"1993-12-17","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"nitazoxanide","drugSlug":"nitazoxanide","fdaApproval":"2002-11-22","genericCount":3,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"tenonitrozole","indications":{"approved":[{"name":"Infection by Trichomonas","source":"DrugCentral","snomedId":56335008,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"atovaquone","brandName":"atovaquone","genericName":"atovaquone","approvalYear":"1992","relationship":"same-class"},{"drugId":"trimetrexate","brandName":"trimetrexate","genericName":"trimetrexate","approvalYear":"1993","relationship":"same-class"},{"drugId":"nitazoxanide","brandName":"nitazoxanide","genericName":"nitazoxanide","approvalYear":"2002","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"005345","UNII":"PBQ7WLE1WP","CHEBI":"CHEBI:135042","INN_ID":"5150","RXNORM":"236186","UMLSCUI":"C0771436","ChEMBL_ID":"CHEMBL1082354","KEGG_DRUG":"D07360","DRUGBANK_ID":"DB13659","PUBCHEM_CID":"19646","SNOMEDCT_US":"717106007"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Infectious Disease"],"atcClassification":{"source":"DrugCentral","atcCode":"P01AX08","allCodes":["P01AX08"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Atrican is a small molecule with the synonyms ATRICAN, TENONITROZOL, TENONITROZOLE, and TENONITROZOLE.","enrichmentLevel":5,"visitCount":0,"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T10:58:32.098792+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}