{"id":"tdap-vaccine-ssi","safety":{"commonSideEffects":[{"rate":"null","effect":"Pain, redness, or swelling at the injection site"},{"rate":"null","effect":"Fatigue"},{"rate":"null","effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This vaccine contains inactivated diphtheria, tetanus, and pertussis antigens that are combined with a diphtheria toxoid. When administered, it triggers an immune response, producing antibodies that help protect against these bacterial infections. The vaccine is designed to provide long-term immunity against diphtheria, tetanus, and pertussis.","oneSentence":"The TdaP vaccine SSI works by stimulating the body's immune system to produce antibodies against diphtheria, tetanus, and pertussis.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:37:38.692Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of diphtheria, tetanus, and pertussis in individuals of all ages"}]},"trialDetails":[{"nctId":"NCT02771782","phase":"PHASE4","title":"Influence of BCG on TDaP-IPV Vaccination","status":"UNKNOWN","sponsor":"Radboud University Medical Center","startDate":"2015-01","conditions":"Whooping Cough","enrollment":75},{"nctId":"NCT01033877","phase":"PHASE3","title":"Immunogenicity and Safety of Tetanus, Diphtheria and Mono Component Acellular Pertussis (TdaP) Vaccine in Comparison to Tetanus and Diphtheria (Td) Vaccine When Given as Booster Vaccinations to Adults","status":"COMPLETED","sponsor":"Statens Serum Institut","startDate":"2010-01","conditions":"Healthy","enrollment":802}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"TdaP vaccine SSI","genericName":"TdaP vaccine SSI","companyName":"Statens Serum Institut","companyId":"statens-serum-institut","modality":"Biologic","firstApprovalDate":"","aiSummary":"The TdaP vaccine SSI works by stimulating the body's immune system to produce antibodies against diphtheria, tetanus, and pertussis. Used for Prevention of diphtheria, tetanus, and pertussis in individuals of all ages.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}