{"id":"tc-99m-filtered-sulfur-colloid","safety":{"commonSideEffects":[{"rate":null,"effect":"Allergic reaction"},{"rate":null,"effect":"Radiation exposure"}]},"_chembl":{"chemblId":"CHEMBL1201529","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The sulfur colloid particles are filtered to a specific size range and labeled with technetium-99m, a gamma-emitting radioisotope. When injected intravenously, these particles are rapidly taken up by macrophages in the liver, spleen, and bone marrow, enabling scintigraphic imaging of these organs and detection of focal lesions or functional abnormalities. The filtered preparation ensures optimal particle size for hepatic uptake while minimizing bone marrow and splenic uptake.","oneSentence":"Tc-99m filtered sulfur colloid is a radiopharmaceutical that accumulates in the reticuloendothelial system, allowing visualization of organs and tissues via gamma imaging.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:11:17.050Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hepatic imaging and detection of focal liver lesions"},{"name":"Splenic imaging"},{"name":"Bone marrow imaging"},{"name":"Gastroesophageal reflux detection"},{"name":"Gastrointestinal bleeding localization"}]},"trialDetails":[{"nctId":"NCT03199560","phase":"PHASE4","title":"Tilmanocept vs Sulfur Colloid in Sentinel Lymph Node Biopsy","status":"UNKNOWN","sponsor":"Memorial Health University Medical Center","startDate":"2017-06-22","conditions":"Sentinel Lymph Node Biopsy, Breast Cancer","enrollment":86},{"nctId":"NCT00450723","phase":"NA","title":"Thoracoscopic Sentinel Lymph Node Biopsy in Patients With Stage I or Stage II Breast Cancer","status":"COMPLETED","sponsor":"University of Miami","startDate":"2004-05","conditions":"Breast Cancer","enrollment":39}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Tc 99m filtered sulfur colloid","genericName":"Tc 99m filtered sulfur colloid","companyName":"Memorial Health University Medical Center","companyId":"memorial-health-university-medical-center","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Tc-99m filtered sulfur colloid is a radiopharmaceutical that accumulates in the reticuloendothelial system, allowing visualization of organs and tissues via gamma imaging. Used for Hepatic imaging and detection of focal liver lesions, Splenic imaging, Bone marrow imaging.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}