{"id":"tafluprost-15-g-ml","safety":{"commonSideEffects":[{"rate":"20-40","effect":"Conjunctival hyperemia"},{"rate":"10-20","effect":"Eye irritation/discomfort"},{"rate":"5-15","effect":"Increased iris pigmentation"},{"rate":"5-10","effect":"Eyelash growth (hypertrichosis)"},{"rate":"5-15","effect":"Foreign body sensation"}]},"_chembl":{"chemblId":"CHEMBL1963683","moleculeType":"Small molecule","molecularWeight":"452.54"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Tafluprost binds to prostaglandin F receptors in the eye, primarily enhancing drainage of aqueous humor through the uveoscleral (unconventional) pathway. This increased outflow reduces intraocular pressure, which is the primary pathogenic factor in glaucoma and ocular hypertension. The drug is administered as an ophthalmic solution directly to the affected eye.","oneSentence":"Tafluprost is a prostaglandin F (FP) receptor agonist that increases uveoscleral outflow of aqueous humor to reduce intraocular pressure.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:10:55.769Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Open-angle glaucoma"},{"name":"Ocular hypertension"}]},"trialDetails":[{"nctId":"NCT03204487","phase":"PHASE4","title":"A Study on the Effect of Changing From Preserved Prostaglandin Formulations to Preservative Free Tafluprost on Tear Film Thickness","status":"COMPLETED","sponsor":"Ordination Dr. Hommer","startDate":"2016-05-10","conditions":"Glaucoma, Open-Angle, Ocular Hypertension","enrollment":30}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Tafluprost 15µg/ml","genericName":"Tafluprost 15µg/ml","companyName":"Ordination Dr. Hommer","companyId":"ordination-dr-hommer","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Tafluprost is a prostaglandin F (FP) receptor agonist that increases uveoscleral outflow of aqueous humor to reduce intraocular pressure. Used for Open-angle glaucoma, Ocular hypertension.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}