{"id":"systematic-rai-treatment","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Thyroiditis"},{"rate":"5-10%","effect":"Salivary gland damage"},{"rate":"5-10%","effect":"Hypothyroidism"}]},"_chembl":{"chemblId":"CHEMBL7257","moleculeType":"Small molecule","molecularWeight":"218.30"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This process works by allowing the radioactive iodine to be taken up by the thyroid cells, which then absorb the radiation and die. The radioactive iodine is selectively taken up by the thyroid cells due to the presence of iodine transport mechanisms, allowing for targeted therapy with minimal damage to surrounding healthy tissues.","oneSentence":"Systematic RAI-treatment involves the use of radioactive iodine to target and destroy thyroid cancer cells.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:37:03.769Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Thyroid cancer"}]},"trialDetails":[{"nctId":"NCT04290663","phase":"PHASE3","title":"Systematic Radioiodine Administration Versus Decision of Radioiodine Treatment Guided by a Post-operative Work-up","status":"RECRUITING","sponsor":"Centre Francois Baclesse","startDate":"2020-03-02","conditions":"Thyroid Cancer, Intermediate Risk","enrollment":476}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Systematic RAI-treatment","genericName":"Systematic RAI-treatment","companyName":"Centre Francois Baclesse","companyId":"centre-francois-baclesse","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Systematic RAI-treatment involves the use of radioactive iodine to target and destroy thyroid cancer cells. Used for Thyroid cancer.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}