{"id":"systane-ultra-ud","safety":{"commonSideEffects":[{"rate":null,"effect":"Temporary blurred vision"},{"rate":null,"effect":"Eye irritation or discomfort"},{"rate":null,"effect":"Ocular hyperemia"}]},"_chembl":{"chemblId":"CHEMBL24646","moleculeType":"Small molecule","molecularWeight":"334.38"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The formulation contains a combination of lubricating agents (polyethylene glycol 400 and propylene glycol) along with an electrolyte solution that mimics natural tears. It provides sustained hydration and protection to the cornea and conjunctiva, reducing friction and irritation associated with dry eye disease. The unit dose (UD) format ensures sterility and convenience for single-use application.","oneSentence":"Systane Ultra UD is an artificial tear solution that lubricates and protects the ocular surface to relieve dry eye symptoms.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:10:30.988Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye disease / Keratoconjunctivitis sicca"}]},"trialDetails":[{"nctId":"NCT03319420","phase":"PHASE4","title":"Evaluate the Efficacy and Safety of LO2A Eye Drops for Symptomatic Improvement of Dry Eye in Patients With Sjögren's Syndrome","status":"COMPLETED","sponsor":"Ocuwize LTD","startDate":"2018-03-29","conditions":"Dry Eye Due to Sjögren's Syndrome","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Systane Ultra UD","genericName":"Systane Ultra UD","companyName":"Ocuwize LTD","companyId":"ocuwize-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Systane Ultra UD is an artificial tear solution that lubricates and protects the ocular surface to relieve dry eye symptoms. Used for Dry eye disease / Keratoconjunctivitis sicca.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}