{"id":"systane-ultra-multidose","safety":{"commonSideEffects":[{"rate":"null","effect":"Eye irritation"}]},"_chembl":{"chemblId":"CHEMBL990","moleculeType":"Small molecule","molecularWeight":"317.48"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It does this by creating a protective barrier on the surface of the eye, helping to retain moisture and reduce friction between the eyelid and cornea. This can help to alleviate symptoms of dry eye syndrome, such as grittiness, burning, and blurred vision.","oneSentence":"Systane Ultra Multidose lubricates the eyes to help relieve dryness and irritation.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:37:02.751Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Relief of dryness and irritation associated with dry eye syndrome"}]},"trialDetails":[{"nctId":"NCT04393441","phase":"PHASE3","title":"Efficacy and Safety of a New Artificial Tear Formulation Compared With Systane Ultra Multidose in Participants With Dry Eye Disease","status":"COMPLETED","sponsor":"Allergan","startDate":"2020-06-29","conditions":"Dry Eye Disease (DED)","enrollment":400},{"nctId":"NCT03223909","phase":"PHASE4","title":"Efficacy and Safety of the Ophthalmic Solution PRO-087 Versus Systane ® Ultra and Ultra Preservative Free (087LATAMFIV)","status":"COMPLETED","sponsor":"Laboratorios Sophia S.A de C.V.","startDate":"2016-10-13","conditions":"Dry Eye Syndrome","enrollment":326}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Systane Ultra Multidose","genericName":"Systane Ultra Multidose","companyName":"Allergan","companyId":"allergan","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Systane Ultra Multidose is a small molecule artificial tear formulation used to treat Dry Eye Disease and Dry Eye Syndrome. It is compared to other artificial tear formulations in clinical trials, such as REFRESH PLUS, for its efficacy and safety.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}