{"id":"systane-pro","safety":{"commonSideEffects":[{"rate":null,"effect":"Mild ocular irritation"},{"rate":null,"effect":"Temporary blurred vision"},{"rate":null,"effect":"Eye redness"}]},"_chembl":{"chemblId":"CHEMBL216386","moleculeType":"Protein","molecularWeight":"1119.29"},"_dailymed":{"setId":"a12baf3d-f22b-4c9f-a4c8-4e0d09f6d6f1","title":"SYSTANE PRO PF (PROPYLENE GLYCOL) EMULSION [ALCON LABORATORIES, INC.]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Systane PRO contains a proprietary formulation of lubricants and demulcents designed to coat and protect the cornea and conjunctiva. The formulation includes polyethylene glycol and propylene glycol as active lubricating agents, along with other excipients that help stabilize the tear film and reduce evaporation. It is indicated for temporary relief of dry eye symptoms by maintaining ocular surface hydration.","oneSentence":"Systane PRO is an over-the-counter lubricating eye drop that provides sustained moisture and relief to the ocular surface.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:10:31.586Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Temporary relief of dry eye symptoms and discomfort"}]},"trialDetails":[{"nctId":"NCT07243275","phase":"PHASE4","title":"SYSTANE® PRO vs. MIEBO™ in Dry Eye Disease","status":"RECRUITING","sponsor":"Indiana University","startDate":"2026-02-18","conditions":"Dry Eye Disease (DED)","enrollment":260},{"nctId":"NCT07451184","phase":"PHASE4","title":"Comparison of Ocular Lubricants in People With Symptoms of Dry Eye","status":"RECRUITING","sponsor":"University of Waterloo","startDate":"2026-02-23","conditions":"Dry Eye Symptoms","enrollment":100},{"nctId":"NCT06975891","phase":"PHASE4","title":"Performance of Systane PRO Versus Refresh Optive Mega-3","status":"RECRUITING","sponsor":"Scripps Poway Eyecare and Optometry","startDate":"2025-05-15","conditions":"Dry Eye","enrollment":35}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Systane PRO","genericName":"Systane PRO","companyName":"Scripps Poway Eyecare and Optometry","companyId":"scripps-poway-eyecare-and-optometry","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Systane PRO is an over-the-counter lubricating eye drop that provides sustained moisture and relief to the ocular surface. Used for Temporary relief of dry eye symptoms and discomfort.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}