{"id":"systane-complete-pf","safety":{"commonSideEffects":[{"rate":null,"effect":"Ocular irritation"},{"rate":null,"effect":"Blurred vision"},{"rate":null,"effect":"Eye discomfort"}]},"_chembl":{"chemblId":"CHEMBL484929","moleculeType":"Small molecule","molecularWeight":"452.29"},"_dailymed":{"setId":"798ffdde-1dba-4a3f-a0b6-937f9e958cca","title":"SYSTANE COMPLETE PF (PROPYLENE GLYCOL EMULSION) EMULSION [ALCON LABORATORIES, INC.]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This preservative-free (PF) formulation combines multiple lubricating agents including glycerin, propylene glycol, and mineral oil to provide sustained moisture and protection to the cornea and conjunctiva. The multi-component formulation mimics natural tear composition to reduce friction, improve tear film stability, and provide relief from dry eye discomfort.","oneSentence":"Systane Complete PF is an artificial tear solution that lubricates and protects the ocular surface to relieve dry eye symptoms.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:10:37.915Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye disease / Keratoconjunctivitis sicca"}]},"trialDetails":[{"nctId":"NCT06219577","phase":"PHASE4","title":"Subjective and Objective Performance of Systane Complete Multi-Dose PF Versus Walgreen's Lubricant Balance","status":"COMPLETED","sponsor":"Scripps Poway Eyecare and Optometry","startDate":"2024-01-18","conditions":"Dry Eye","enrollment":70},{"nctId":"NCT05705518","phase":"PHASE4","title":"Artificial Tears, Tear Lipids and Tear Film Dynamics","status":"COMPLETED","sponsor":"University of California, Berkeley","startDate":"2023-01-30","conditions":"Dry Eye","enrollment":81},{"nctId":"NCT06686368","phase":"PHASE4","title":"Comparative Efficacy Study to Demonstrate the Non-inferiority of I-DROP® MGD Versus 2 Competitor Eye Drops in Managing Evaporative Dry Eye","status":"NOT_YET_RECRUITING","sponsor":"I-MED Pharma","startDate":"2024-11-15","conditions":"Evaporative Dry Eye Disease","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Systane Complete PF","genericName":"Systane Complete PF","companyName":"University of California, Berkeley","companyId":"university-of-california-berkeley","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Systane Complete PF is an artificial tear solution that lubricates and protects the ocular surface to relieve dry eye symptoms. Used for Dry eye disease / Keratoconjunctivitis sicca.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}